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Postion:Product Catalog >SB-284851-BT
SB-284851-BT
  • SB-284851-BT

SB-284851-BT NEW

Price $1520 $1980 $2500
Package 25mg 50mg 100mg
Min. Order:
Supply Ability: 10g
Update Time: 2025-04-30

Product Details

Product Name: SB-284851-BT CAS No.: 219769-23-0
Supply Ability: 10g Release date: 2025/04/30

Product Introduction

Bioactivity

NameSB-284851-BT
DescriptionSB-284851-BT is a chemical compound that serves as an inhibitor of BRD4, p38α, and BRDT, exhibiting varying degrees of affinity and inhibition for each. Specifically, it inhibits BRD4-BD1 with an IC50 value of 1.7 μM, p38α with a Kd of 0.47 nM, BRDT (1) with an IC50 value of 18 μM, and BRD4 (1) with an IC50 value of 3.7 μM. By targeting p38α, SB-284851-BT effectively reduces IL-8 production and, through inhibiting BRD4, down-regulates both the c-Myc and NF-κB gene pathways, crucial in cancer pathways. Additionally, SB-284851-BT is designed to combine with the bromine domain and extra terminal (BET) proteins.
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
KeywordsSB-284851-BT | ATZ1993 | ATZ 1993

Company Profile Introduction

TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds. 170+ Compound Libraries, 10000+ Noval Small Molecucles,16000+ Nature Compounds TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.

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