SB 206553 hydrochloride NEW
| Price | $209 | $528 |
| Package | 5mg | 25mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-07-27 |
Product Details
| Product Name: SB 206553 hydrochloride | CAS No.: 1197334-04-5 |
| Purity: 99.56% | Supply Ability: 10g |
| Release date: 2025/07/27 |
Product Introduction
Bioactivity
| Name | SB 206553 hydrochloride |
| Description | SB 206553 hydrochloride is an orally active, selective, and efficient 5-HT2C inverse agonist and 5-HT2C/5-HT2B receptor antagonist with anti-anxiety activity. It is useful in neurological disease research. |
| In vitro | SB 206553 hydrochloride (50 μM) prevented the promotion of mEPSC induced by the application of α-Me-5HT (10 μM), while the rise and decay time constants of mEPSC administered by α-Me-5HT remained unchanged in the presence of SB 206553 hydrochloride. [1] |
| In vivo | Intraperitoneal administration of SB 206553 hydrochloride (1-10 mg/kg) caused a dose-dependent increase in DA release from the accumbens and striatum in rats. [2] SB 206553 hydrochloride (1-10mg/kg), only 10mg/kg, enhanced c-Fos expression in STN, striatum (except dorsomedial part), NAcc, inner surface nucleus, substantia nigra reticularis (SNr) and densa (SNc), and ventral tegmental area. [3] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 25 mg/mL (76.03 mM), Sonication is recommended. |
| Keywords | SB-206553 Hydrochloride |
| Inhibitors Related | Stavudine | 5-Fluorouracil | Emtricitabine | Kaempferol | Dolutegravir intermediate-1 | Dextran sulfate sodium salt (MW 4500-5500) | Dimethyl fumarate | Lamivudine | Chloroquine phosphate | Valproic Acid | Decanedioic acid | Tenofovir |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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