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Postion:Product Catalog >Satraplatin
Satraplatin
  • Satraplatin

Satraplatin NEW

Price $100 $247 $396
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2025-07-27

Product Details

Product Name: Satraplatin CAS No.: 129580-63-8
Purity: 98.25% Supply Ability: 10g
Release date: 2025/07/27

Product Introduction

Bioactivity

NameSatraplatin
DescriptionSatraplatin (BMS182751) is an orally available antineoplastic platinum(IV) complex.Satraplatin has a favorable toxicity profile and appears to have clinical activity against a variety of malignancies.
Cell ResearchCDDP-resistant (KB-R) cells and parental cells (KB) pair were used. Viability was assessed using the MTT and clonogenic assay. Real-time polymerase chain reaction (PCR), glutathione (GSH) assay, and flow cytometric analysis were used for further assessment[1].
In vitroKB-R cells did not show cross-resistance to satraplatin. The expression status of almost all transporters was upregulated in the KB-R cells. There was no difference in the GSH levels between the KB and KB-R cells. Flow cytometric analysis indicated that with satraplatin the G2/M phase was arrested in the KB-R cells. KB-R cells contain enriched side population cells[1].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility InformationDMSO : 33 mg/mL (65.96 mM), DMSO inactivates the activity of Satraplatin.
KeywordsSatraplatin | JM-216 | JM 216 | Inhibitor | inhibit | DNAAlkylator | DNAAlkylation | DNA Alkylator/Crosslinker | DNA Alkylator | DNA Alkylation | DNA Alkylating | Crosslinker | BMY-45594 | BMY 45594 | BMS-182751 | BMS 182751
Inhibitors RelatedCyclophosphamide hydrate | Lomustine | Bendamustine hydrochloride | Busulfan | N-Nitroso-N-methylurea | Ifosfamide | Streptozocin | Temozolomide | Cyclophosphamide | Methyl methanesulfonate | Carboplatin | Cisplatin

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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