S19-1035 NEW
| Price | $33 | $50 | $103 |
| Package | 5mg | 10mg | 25mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-04-28 |
Product Details
| Product Name: S19-1035 | Purity: 100% |
| Supply Ability: 10g | Release date: 2025/04/28 |
Product Introduction
Bioactivity
| Name | S19-1035 |
| Description | S19-1035 is a potent and specific inhibitor of aldo-keto reductase 1C3 (AKR1C3), displaying an inhibitory concentration (IC50) of 3.04 nM. It is primarily utilized in tumor research. |
| In vitro | S19-1035 demonstrates low cytotoxicity (0-100 μM ; 72 h or 96 h) and limited antitumor efficacy when used alone.[1] S19-1035 significantly reverses the resistance of doxorubicin-resistant breast cancer cell lines when administered at 10 μM for 8 days.[1] |
| In vivo | Setrobuvir (200, 400, and 800 mg) BID were -2.1, -2.2, and -2.9 log10 IU/mL, respectively (vs ≤0.1 log10 IU/mL with placebo).[3] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 112.5 mg/mL (315.3 mM), Sonication and heating to 60℃ are recommended. |
| Keywords | AKR1C3 |
| Inhibitors Related | Carvedilol phosphate hemihydrate | ASP-9521 | HTS07545 | Metronidazole | Resveratrol | Pasiniazid | Dicoumarol | NAD+ | Apocynin | Triclosan | AKR1C1-IN-1 | Setanaxib |
| Related Compound Libraries | Bioactive Compound Library | Anti-Breast Cancer Compound Library | Inhibitor Library | Mitochondria-Targeted Compound Library | Metabolism Compound Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library | Anti-Cancer Active Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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