(S)-Carvedilol NEW
| Price | $1350 | $1760 | $2500 |
| Package | 25mg | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-07-20 |
Product Details
| Product Name: (S)-Carvedilol | CAS No.: 95094-00-1 |
| Supply Ability: 10g | Release date: 2025/07/20 |
Product Introduction
Bioactivity
| Name | (S)-Carvedilol |
| Description | (S)-Carvedilol is a non-selective β/α-1 blocker.It exerts protection against the vascular or cardiac toxicity of Doxorubicin (DOX). |
| In vitro | (S)-Carvedilol exhibits beta-receptor blocking activity that is approximately 100 times more potent than that of its enantiomer (R)-Carvedilol, though both enantiomers demonstrate equal efficacy as alpha-blockers. Treatment with (S)-Carvedilol markedly enhances the expression of p-eNOS in HUVECs. Additionally, (S)-Carvedilol effectively reduces Doxorubicin (DOX)-induced cell death, apoptotic alterations, and depletion of mitochondrial membrane potential. It also mitigates oxidative stress by increasing superoxide dismutase and catalase activity, while reducing malondialdehyde levels and reactive oxygen species, mediated through the PI3K/AKT/eNOS pathway in vitro. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | β/α-1 adrenergic receptor | Carvedilol | BM-14190 | BM14190 | BM 14190 | (S)Carvedilol | (S) Carvedilol |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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