Rp-cAMPS sodium NEW
| Price | $299 |
| Package | 1mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-07-16 |
Product Details
| Product Name: Rp-cAMPS sodium | CAS No.: 142439-94-9 |
| Purity: 99.71% | Supply Ability: 10g |
| Release date: 2025/07/16 |
Product Introduction
Bioactivity
| Name | Rp-cAMPS sodium |
| Description | Rp-cAMPS sodium is a phosphorothioate analog of cAMP, a protein kinase A inhibitor and a membrane-permeable cAMP antagonist that inhibits cAMP-dependent protein kinases by blocking cAMP-induced conformational transitions, and can be used in the study of cardiovascular diseases. |
| In vitro | METHODS: To measure the inhibitory effect of Rp-cAMPS sodium on purified type II cAMP-dependent protein kinase, different concentrations of Rp-cAMPS sodium were added, and their impact on cAMP-induced phosphotransferase activity was observed. RESULTS: Rp-cAMPS sodium binds to cAMP but does not cause enzyme dissociation, thereby inhibiting the activity of the phosphotransferase[2]. |
| In vivo | METHODS: To investigate the effect of Rp-cAMPS sodium on synaptic transmission in a rat arthritis model, particularly its modulation of PB-CeLC and BLA-CelC synapses, EPSCs were evoked by stimulating the PB-CeLC and BLA-CelC synapses, and the changes before and after treatment were compared. RESULTS: Treatment with Rp-cAMPS sodium (10 μM, 15 minutes) significantly reduced the evoked single-synaptic EPSCs at the PB-CeLC and BLA-CelC synapses [2]. |
| Storage | store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | H2O : 80 mg/mL (544.59 mM), Sonication is recommended. |
| Keywords | RpcAMPS sodium salt | Rp-cAMPS sodium | Rp cAMPS sodium salt | pka | cAMP |
| Inhibitors Related | Daphnetin | Capivasertib | Bithionol | GSK180736A | Ellagic acid | Acefylline | Ro-3306 | Staurosporine | 8-Bromo-cAMP sodium salt | Bucladesine sodium | Fasudil hydrochloride | JAK1/2/3 Inhibitor 1 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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