
Quinotolast sodium NEW
Price | $1650 | $2150 | $3100 |
Package | 25mg | 50mg | 100mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2025-07-21 |
Product Details
Product Name: Quinotolast sodium | CAS No.: 101193-62-8 |
Supply Ability: 10g | Release date: 2025/07/21 |
Product Introduction
Bioactivity
Name | Quinotolast sodium |
Description | Quinotolast sodium inhibits histamine, LTC4 and PGD2 release in a concentration-dependent manner in the concentration range of 1-100 μg/mL. |
In vitro | Quinotolast significantly inhibits PGD2 and LTC4 release. Quinotolast inhibits PGD2 release by 100% and LTC4 release by 54%. The inhibitory effect of Quinotolast on histamine release from dispersed lung cells is largely independent of the preincubation period, no tachyphylaxis being observed. Quinotolast shows a significant inhibition of inflammatory mediators from human dispersed lung cells[1]. |
In vivo | Quinotolast is given i.v. to rats, Quinotolast, dose-dependently inhibits PCA. The doses of Quinotolast required to inhibit the reaction by 50% (ED50) is 0.0063 mg/kg. Given p.o.[2].Quinotolast potently inhibits such type I allergic reactions as passive cutaneous anaphylaxis (PCA) and anaphylactic bronchoconstriction in rats by both intravenous and oral dosing. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Keywords | Quinotolast sodium | PGD2 | LTC4 | Histamine | FR-71021 | FR 71021 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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TargetMol Chemicals Inc.
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- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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