Pseudocoptisine chloride NEW
| Price | $67 | $163 | $247 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-04-29 |
Product Details
| Product Name: Pseudocoptisine chloride | CAS No.: 30044-78-1 |
| Purity: 98.17% | Supply Ability: 10g |
| Release date: 2025/04/29 |
Product Introduction
Bioactivity
| Name | Pseudocoptisine chloride |
| Description | Pseudocoptisine chloride (Isocoptisine chloride) is isolated from Corydalis Tuber with anti-inflammatory and anti-amnestic properties. Pseudocoptisine chloride inhibits acetylcholinesterase (AChE) activity (IC50 = 12.8 μM). |
| In vitro | In RAW264.7 cells, Pseudocoptisine chloride (0, 60, 90 μM; 1 hour) inhibited LPS-induced NO production in a dose-dependent manner[1]. Pseudocoptisine chloride reduced levels of the pro-inflammatory mediators, such as, iNOS, COX-2, TNF-alpha, and IL-6 through the inhibition of NF-kappaB activation via the suppression of ERK and p38 phosphorylation. Pseudocoptisine chloride (30-90 μM; 1 hour) significantly reduced the LPS-induced TNF-α and IL-6 production and their mRNA expressions[2]. |
| In vivo | Pseudocoptisine chloride (2.0 mg/kg, p.o.) showed anti-amnesic activities on the learning and memory impairments induced by scopolamine (1.0 mg/kg, i.p.) and significantly reverses cognitive impairments in mice by passive avoidance test[2]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 1 mg/mL (2.81 mM), Sonication and heating to 60℃ are recommended. |
| Keywords | RAW 264.7 | Pseudocoptisine Chloride | Pseudocoptisine chloride | Pseudocoptisine | pro-inflammatory | Isocoptisine Chloride | Isocoptisine | Inhibitor | inhibit | cytokines | Cholinesterase (ChE) | anti-inflammatory | anti-amnestic | AChE |
| Inhibitors Related | 1-Naphthyl acetate | DL-Menthol | Ethyl (triphenylphosphoranylidene) acetate | 4-Methylbenzylidene camphor | Isoeugenol acetate | Diethyltoluamide | sn-Glycero-3-phosphocholine | Nizatidine | Coumaran | Methyl tridecanoate | Trimethylammonium chloride | Trimyristin |
| Related Compound Libraries | Anti-Neurodegenerative Disease Compound Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Alkaloid Natural Product Library | Selected Plant-Sourced Compound Library | Anti-Inflammatory Traditional Chinese Medicine Compound Library | Natural Product Library | Inhibitor Library | Natural Product Library for HTS | Anti-Aging Compound Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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