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Postion:Product Catalog >Analytical Chemistry>Standard>Pharmaceutical Impurity Reference Standards>Potassium trichloroammineplatinate (II)
Potassium trichloroammineplatinate (II)
  • Potassium trichloroammineplatinate (II)
  • Potassium trichloroammineplatinate (II)
  • Potassium trichloroammineplatinate (II)
  • Potassium trichloroammineplatinate (II)
  • Potassium trichloroammineplatinate (II)

Potassium trichloroammineplatinate (II) NEW

Price Get Latest Price
Package 1kg 25kg
Min. Order: 1kg
Supply Ability: 1000kg
Update Time: 2025-07-30

Product Details

Product Name: Potassium trichloroammineplatinate (II) CAS No.: 13820-91-2
Min. Order: 1kg Purity: 99.2%
Supply Ability: 1000kg Release date: 2025/07/30

Potassium trichloroammineplatinate(II) is a coordination compound with the formula K[Pt(NH?)Cl?]. Here's a breakdown of its key features:

Composition:

    • Three chloride ions (Cl?)

    • One ammine ligand (NH? - neutral ammonia molecule bound via nitrogen).

    • Central Metal Ion: Platinum(II) (Pt2?), indicating a +2 oxidation state.

    • Ligands:

    • Counterion: Potassium ion (K?) to balance the charge of the complex anion [Pt(NH?)Cl?]?.

      Structure:

    • trans-[Pt(NH?)Cl?]?: The ammonia ligand is opposite a chloride ligand. This is the more common and stable isomer.

    • cis-[Pt(NH?)Cl?]?: The ammonia ligand is adjacent to two chlorides. This isomer is less stable and less common.

    • Pt(II) has a d? electron configuration, favoring a square planar geometry.

    • The complex anion [Pt(NH?)Cl?]? has the NH? and Cl? ligands arranged around the central Pt2? ion in a square plane.

    • Isomers: Two isomers are possible:

      Properties:

    • Typically appears as a yellow or yellowish crystalline solid.

    • Soluble in water (due to the potassium ion).

    • The Pt(II) center is relatively inert but can undergo ligand substitution reactions.

      Synthesis:

    • It is commonly prepared by the reaction of potassium tetrachloroplatinate(II) (K?[PtCl?]) with ammonia (NH?):
      K?[PtCl?] + NH? → K[Pt(NH?)Cl?] + KCl

    • The specific isomer formed (trans or cis) can be influenced by reaction conditions like concentration, temperature, and solvent.

      Significance:

    • Precursor: It serves as a key starting material for synthesizing other important platinum(II) complexes, particularly those relevant to medicinal chemistry.

    • Cisplatin Chemistry: It is a direct precursor to cisplatin ([Pt(NH?)?Cl?]), one of the most important and widely used anticancer drugs. Reacting K[Pt(NH?)Cl?] with more ammonia produces the tetrammine complex [Pt(NH?)?]Cl?, which can then be converted to cisplatin.

    • trans-Platin Analogs: The trans isomer (if isolated) is a precursor to transplatin ([Pt(NH?)?Cl?] trans isomer), which is generally not biologically active as an anticancer drug but is important for comparative studies.

    • Coordination Chemistry: It's a classic example of a square planar Pt(II) ammine/chloro complex studied to understand bonding, isomerism, and reaction mechanisms in inorganic chemistry.

In summary: Potassium trichloroammineplatinate(II) (K[Pt(NH?)Cl?]) is a yellow, water-soluble potassium salt of the trichloroammineplatinate(II) anion. It exists as isomers (trans being predominant) and is primarily significant as a crucial synthetic intermediate, especially for preparing platinum-based anticancer drugs like cisplatin.

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Company Profile Introduction

Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical & its intermediates, Food/Feed additives, Fine chemicals in distributing the products of our own company and affiliated enterprises, are the members of Hubei E-commerce Chamber. Our company has professional persons who major in chemical R&D and sicentific management, supply fine chemical products with high quality and close service, also supply custom-tailored products according to our clients' requirement. We have a positive and self-motivated management work team with a common philosophy, caring and commitment through teamwork, our team strive to achieve success in delighting our clients and ourselves. Since Wuhan Fortuna Chemical Co., Ltd founded, we continuously innovate our products and improve our service, sales network. Hence, we initiate the first sale mode on net in China, which is the retail trade of small package bring along wholesale of diversified management modes. Our products are exported widely to South Korea, Vietnam, Australia, Europe and South America, highly recommended by our clients.We insist on the management creed “Market is our compass, Quality is our life, Credit is our soul”. Clients’ trust is our forward powder, their satisfaction is our struggling goal.

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