
Potassium trichloroammineplatinate (II) NEW
Price | Get Latest Price | |
Package | 1kg | 25kg |
Min. Order: | 1kg |
Supply Ability: | 1000kg |
Update Time: | 2025-07-30 |
Product Details
Product Name: Potassium trichloroammineplatinate (II) | CAS No.: 13820-91-2 |
Min. Order: 1kg | Purity: 99.2% |
Supply Ability: 1000kg | Release date: 2025/07/30 |
Potassium trichloroammineplatinate(II) is a coordination compound with the formula K[Pt(NH?)Cl?]. Here's a breakdown of its key features:
Composition:
Three chloride ions (Cl?)
One ammine ligand (NH? - neutral ammonia molecule bound via nitrogen).
Central Metal Ion: Platinum(II) (Pt2?), indicating a +2 oxidation state.
Ligands:
Counterion: Potassium ion (K?) to balance the charge of the complex anion [Pt(NH?)Cl?]?.
Structure:
trans-[Pt(NH?)Cl?]?: The ammonia ligand is opposite a chloride ligand. This is the more common and stable isomer.
cis-[Pt(NH?)Cl?]?: The ammonia ligand is adjacent to two chlorides. This isomer is less stable and less common.
Pt(II) has a d? electron configuration, favoring a square planar geometry.
The complex anion [Pt(NH?)Cl?]? has the NH? and Cl? ligands arranged around the central Pt2? ion in a square plane.
Isomers: Two isomers are possible:
Properties:
Typically appears as a yellow or yellowish crystalline solid.
Soluble in water (due to the potassium ion).
The Pt(II) center is relatively inert but can undergo ligand substitution reactions.
Synthesis:
It is commonly prepared by the reaction of potassium tetrachloroplatinate(II) (K?[PtCl?]) with ammonia (NH?):
K?[PtCl?] + NH? → K[Pt(NH?)Cl?] + KClThe specific isomer formed (trans or cis) can be influenced by reaction conditions like concentration, temperature, and solvent.
Significance:
Precursor: It serves as a key starting material for synthesizing other important platinum(II) complexes, particularly those relevant to medicinal chemistry.
Cisplatin Chemistry: It is a direct precursor to cisplatin ([Pt(NH?)?Cl?]), one of the most important and widely used anticancer drugs. Reacting K[Pt(NH?)Cl?] with more ammonia produces the tetrammine complex [Pt(NH?)?]Cl?, which can then be converted to cisplatin.
trans-Platin Analogs: The trans isomer (if isolated) is a precursor to transplatin ([Pt(NH?)?Cl?] trans isomer), which is generally not biologically active as an anticancer drug but is important for comparative studies.
Coordination Chemistry: It's a classic example of a square planar Pt(II) ammine/chloro complex studied to understand bonding, isomerism, and reaction mechanisms in inorganic chemistry.
In summary: Potassium trichloroammineplatinate(II) (K[Pt(NH?)Cl?]) is a yellow, water-soluble potassium salt of the trichloroammineplatinate(II) anion. It exists as isomers (trans being predominant) and is primarily significant as a crucial synthetic intermediate, especially for preparing platinum-based anticancer drugs like cisplatin.
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