
Pomalidomide-amido-PEG3-C2-NH2 NEW
Price | $79 | $128 |
Package | 2mg | 5mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2025-07-19 |
Product Details
Product Name: Pomalidomide-amido-PEG3-C2-NH2 | CAS No.: 2328070-52-4 |
Supply Ability: 10g | Release date: 2025/07/19 |
Product Introduction
Bioactivity
Name | Pomalidomide-amido-PEG3-C2-NH2 |
Description | Pomalidomide-amido-PEG3-C2-NH2, known as Cereblon Ligand-Linker Conjugates 22, is a synthesized E3 ligase ligand-linker conjugate designed for use in PROTAC technology. It consists of the Pomalidomide-based cereblon ligand and a 3-unit PEG linker. [1] |
In vitro | Pomalidomide-amido-PEG3-C2-NH2 (Compound 5b) is a precursor for synthesizing BI-3663, a cereblon-based molecule that degrades focal adhesion tyrosine kinase (PTK2) in human hepatocellular carcinoma (HCC) cell lines. It achieves over 80% degradation in 11 HCC cell lines, with a median DC50 of 30 nM[1]. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Keywords | Pomalidomide-amido-PEG3-C2-NH2 | Pomalidomide-amido-PEG-3-C2-NH2 | PomalidomideamidoPEG3C2NH2 | Pomalidomide amido PEG3 C2 NH2 | Cereblon |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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