PKC-IN-1 NEW
| Price | $198 | $347 | $1140 |
| Package | 2mg | 5mg | 25mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-05-12 |
Product Details
| Product Name: PKC-IN-1 | CAS No.: 1046787-18-1 |
| Purity: 98.79% | Supply Ability: 10g |
| Release date: 2025/05/12 |
Product Introduction
Bioactivity
| Name | PKC-IN-1 |
| Description | PKC-IN-1 is an ATP-competitive and reversible conventional PKC enzymes inhibitor (PKCα, PKCβI, PKCβII, PKCθ, PKCγ, PKC mu and PKCε with IC50s of 2.3, 8.1, 7.6, 25.6, 57.5, 314, 808 nM, respectively). |
| In vitro | PKC-IN-1 is a potent, ATP-competitive, and reversible of conventional PKC enzymes (PKCα, PKCβI, PKCβII, PKCθ, PKCγ, PKC mu and PKCε with Kis of 5.3 and 10.4 nM for human PKCβ and PKCα, and IC50s of 2.3, 8.1, 7.6, 25.6, 57.5, 314, 808 nM, respectively) [1]. |
| In vivo | In Lewis rats, PKC-IN-1 dose-dependently and significantly reduces maximum EAE severity and end severity in the autoimmune encephalitis (EAE) model [1]. |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 25 mg/mL (49.94 mM), Sonication is recommended. |
| Keywords | Protein kinase C | PKCθ | PKCε | PKCγ | PKCβ2 | PKCβ | PKCα | PKC-IN-1 | PKCIN1 | PKC IN 1 | PKC | Inhibitor | inhibit | Human PKCθ | Human PKCε | Human PKCγ | Human PKCβII | Human PKCβI | Human PKCβ | Human PKCα | Human PKC mu |
| Inhibitors Related | Daphnetin | Darovasertib | Ellagic acid | α-Vitamin E | Ro-3306 | Staurosporine | Methyl-Hesperidin | N-Desmethyltamoxifen hydrochloride | Fasudil hydrochloride | Mitoxantrone dihydrochloride | Myricitrin | R59949 |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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