Piperoxan hydrochloride NEW
| Price | $59 | $88 | $137 |
| Package | 5mg | 10mg | 25mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-05-14 |
Product Details
| Product Name: Piperoxan hydrochloride | CAS No.: 135-87-5 |
| Purity: 99.61% | Supply Ability: 10g |
| Release date: 2025/05/14 |
Product Introduction
Bioactivity
| Name | Piperoxan hydrochloride |
| Description | Piperoxan hydrochloride (Benodaine hydrochloride) is an α2 adrenoceptor antagonist. Piperoxan (benodaine) is a drug which was the very first antihistamine to be discovered. |
| In vitro | When superfusing the medulla with Piperoxan (50 μM; 5 min) and the pons with artificial cerebrospinal fluid (ACSF), three inactive preparations exhibit low-frequency rhythmic phrenic bursts (2-4 c/min), with the phrenic burst frequency in 12 active preparations significantly increasing to 163±12% of the previous average frequency in the final 3 minutes of Piperoxan application. In active preparations, the impact of norepinephrine (NA) applications (25 μM; 5 min) is assessed under conditions of superfusion with either ACSF (n=8) or α2 adrenoceptor antagonist Piperoxan (50 μM; PIP-ACSF; n=5). Both scenarios of NA application (NA-ACSF alone or combined with PIP-ACSF+NA) lead to a marked increase in phrenic burst frequency. Notably, inhibiting medullary α2 adrenoceptors with Piperoxan significantly enhances this effect: during NA application's fifth minute, phrenic burst frequency escalates to 171±11% with ACSF alone and 234±21% under PIP-ACSF, compared to the baseline control values. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 50 mg/mL (185.34 mM), Sonication is recommended. |
| Keywords | α2 receptor | Piperoxan | Benodaine | AdrenergicReceptor | Adrenergic Receptor |
| Inhibitors Related | Olanzapine | Mirtazapine | Octopamine hydrochloride | Gemfibrozil | Buflomedil hydrochloride | Dexmedetomidine hydrochloride | Phenylephrine hydrochloride | Amitriptyline hydrochloride | Isoprenaline hydrochloride | Trazodone hydrochloride | Mianserin hydrochloride | Doxepin hydrochloride |
| Related Compound Libraries | Bioactive Compound Library | Anti-Neurodegenerative Disease Compound Library | Membrane Protein-targeted Compound Library | Inhibitor Library | Endocrinology-Hormone Compound Library | Anti-Cardiovascular Disease Compound Library | NO PAINS Compound Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | GPCR Compound Library | Anti-Cancer Compound Library | Anti-Hypertension Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
Recommended supplier
| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $0.00/1kg |
VIP1Y
|
Chongqing Soarwin Technology Co., Ltd
|
2025-04-09 | |
| $0.00/1kg |
VIP3Y
|
Wuhan Senwayer Century Chemical Co.,Ltd
|
2022-10-28 | |
| $0.00/1g |
Biopole Pharmatech Co., Ltd.
|
2024-02-04 | ||
| $1.00/1KG |
VIP6Y
|
Career Henan Chemical Co
|
2019-12-25 |
United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
INQUIRY