
PI3K/mTOR Inhibitor-2 NEW
Price | $53 | $148 | $238 |
Package | 1mg | 5mg | 10mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2025-07-17 |
Product Details
Product Name: PI3K/mTOR Inhibitor-2 | CAS No.: 1848242-58-9 |
Purity: 96.16% | Supply Ability: 10g |
Release date: 2025/07/17 |
Product Introduction
Bioactivity
Name | PI3K/mTOR Inhibitor-2 |
Description | PI3K/mTOR Inhibitor-2 is a potent pan inhibitor of PI3K and mTOR with IC50s of 3.4, 34, 16.1, and 4.7 nM for PI3Kα, PI3Kβ, PI3Kδ, PI3Kγ, and mTOR, respectively. PI3K/mTOR Inhibitor-2 demonstrates antitumor activity. |
In vitro | PI3K/mTOR Inhibitor-2 exhibited high enzyme activity against PI3K and mTOR, potent suppression of Akt and p70s6k phosphorylation with IC50s of 11.6 and 89.2 nM in cell assays, and good pharmacokinetic profile[1]. |
In vivo | PI3K/mTOR Inhibitor-2 demonstrated in vivo efficacy in a PC-3M tumor xenograft model[1]. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Solubility Information | DMSO : 55 mg/mL (114.86 mM), Sonication is recommended. |
Keywords | PI3Kδ | PI3Kγ | PI3Kβ | PI3Kα | PI3K/mTOR Inhibitor-2 | PI-3K/mTOR Inhibitor-2 | PI3K/mTOR Inhibitor2 | PI3K/mTOR Inhibitor 2 | PI3K | Phosphoinositide 3-kinase | mTOR | Mammalian target of Rapamycin | Inhibitor | inhibit |
Inhibitors Related | L-Leucine | Myricetin | Erucic acid | Sapanisertib | (2S,3R,4S)-4-Hydroxyisoleucine | 3-Methyladenine | Duvelisib (R enantiomer) hydrochloride | Isoprenaline hydrochloride | Quercetin | Quercetin Dihydrate | Apilimod | Rapamycin |
Related Compound Libraries | Anti-Lung Cancer Compound Library | Glycometabolism Compound Library | Bioactive Compound Library | Kinase Inhibitor Library | Glutamine Metabolism Compound Library | Angiogenesis related Compound Library | Inhibitor Library | Anti-Aging Compound Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | Fluorochemical Library | Anti-Cancer Active Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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