PF-04957325 NEW
| Price | $139 | $247 | $372 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-07-18 |
Product Details
| Product Name: PF-04957325 | CAS No.: 1305115-80-3 |
| Purity: 99.02% | Supply Ability: 10g |
| Release date: 2025/07/18 |
Product Introduction
Bioactivity
| Name | PF-04957325 |
| Description | PF-04957325 is a potent and selective inhibitor of PDE8.PF-04957325 has an IC50 of 0.7 nM for PDE8A and 0.3 nM for PDE8B.PF-04957325 can be used to study autoimmune encephalomyelitis. |
| In vitro | The PDE8 selective inhibitor PF-04957325 exhibits an IC50 of 0.7 nM for PDE8A and 0.2 nM for PDE8B, while its IC50 for all other PDE isoforms is greater than 1.5 μM [3]. Treatment with PF-04957325 in WT Leydig cells or MA10 cells increases steroid production, but has no effect in PDE8A(-/-)/B(-/-) double knockout cells, indicating the drug's specificity [4]. |
| Storage | store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 80 mg/mL (200 mM), Sonication is recommended. |
| Keywords | PF-04957325 | PF04957325 | PF 04957325 | PDE8 |
| Inhibitors Related | Theophylline monohydrate | Pentoxifylline | Diphylline | Acefylline | Roflumilast | Theobromine | Apremilast | Indomethacin | Icariin | Vardenafil hydrochloride | Doxofylline | Sildenafil citrate |
| Related Compound Libraries | Bioactive Compound Library | Inhibitor Library | Anti-Cardiovascular Disease Compound Library | Metabolism Compound Library | Bioactive Compounds Library Max | Fluorochemical Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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