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Postion:Product Catalog >PARPi-FL
PARPi-FL
  • PARPi-FL

PARPi-FL NEW

Price $213
Package 1mg
Min. Order:
Supply Ability: 10g
Update Time: 2025-04-27

Product Details

Product Name: PARPi-FL CAS No.: 1380359-84-1
Purity: 99.73% Supply Ability: 10g
Release date: 2025/04/27

Product Introduction

Bioactivity

NamePARPi-FL
DescriptionPARPi-FL (PARPiFL) is a fluorescent PARP1 inhibitor used for imaging glioblastoma and detecting oral cancer.
In vitroThe IC50 of PARPi-FL for glioblastoma cell lines U87 and U251 was 27.7 ± 1.3 μM and 8.0 ± 1.2 μM, respectively. [1]
In vivoPARPi-FL has a half-life of 24.5 minutes t1/2 in mice. PARPi-FL (2.5 mg/kg) 90 minutes after intravenous administration, the concentration of PARPi-FL in tumors was significantly higher than in muscle or brain, indicating that PARPi-FL was able to generate high-contrast images of tumor tissue in the brain. [1] PARPi-FL can be used for fluorescent-guided tumor resection in a mouse model of oral cancer. [2]
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 40 mg/mL (62.46 mM), Sonication is recommended.
KeywordsPARPi-FL | PARPi FL | Olaparib bodipy FL
Inhibitors Related4'-Methoxychalcone | Niraparib tosylate monohyrate | VPC-70063 | 3-Aminobenzamide | XAV-939 | Niraparib | 3-Methoxybenzamide | NU1025 | Olaparib | Benzamide | Picolinamide | OUL35

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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