午夜插插,噜噜噜影院,啪啪伊人网,欧美熟夫,景甜吻戏视频,男人强操性感蕾丝美女视频在线网站,日本美女跳舞视频

Welcome to chemicalbook!
+1 (818) 612-2111
RFQ
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

RFQ
skype
MY Account
Top
Postion:Product Catalog >Palmitoyl Tripeptide-8
Palmitoyl Tripeptide-8
  • Palmitoyl Tripeptide-8
  • Palmitoyl Tripeptide-8

Palmitoyl Tripeptide-8

Price Get Latest Price
Package 1T 10T 20T
Min. Order: 0.000001T
Supply Ability: 200000000T
Update Time: 2025-07-30

Product Details

Product Name: Palmitoyl Tripeptide-8 CAS No.: 936544-53-5
EC-No.: 000-000-0 Min. Order: 0.000001T
Purity: 99.99% Supply Ability: 200000000T
Release date: 2025/07/30

Chemical Properties

Density 1.20±0.1 g/cm3(Predicted)
pka13.34±0.46(Predicted)
InChIKeyWBHUVOTYPRYBNG-QAXCHELISA-N
SMILESC(N)(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CC1=CC=CC=C1)NC(=O)[C@H](CC1N=CNC=1)NC(=O)CCCCCCCCCCCCCCC


Usage And Synthesis

Description
Palmitoyl tripeptide-8 is a synthetic peptide ester based on a α-melanocyte stimulating hormone (α-MSH), originating from POMC, and it is composed by the sequence N-(1-oxohexadecyl)-L-histidyl-D-phenylalanyl-L-argininamide. Palmitoyl Tripeptide-8 is the product obtained by the reaction of palmitic acid and Tripeptide-8, wherein Tripeptide-8 is a three-residue synthetic peptide consisting of arginine, histidine and phenylalanine[1].
benefits
PalmitoylTripeptide-8 has a high affinity with MC1-R, specific anti-inflammatory activity, inhibit effectively lL-8release induced by UVB, maintain and restore anormal skin sensitivity threshold.Its recommended dosage is 0.3~2.5%.
Synthesis
Palmitoyl Tripeptide-8 can be obtained via a solid-phase peptide synthesis using the fluorenylmethyloxycarbonyl (Fmoc) strategy on an ACT496S2 automated synthesizer with PS-Rink amide (RAM) resin. The deprotection and coupling steps are carried out until the desired sequences are synthesized. Final side-chain deprotection and cleavage from the resin with a cleavage cocktail (trifluoroacetic acid/water/triisopropylsilane) afford palmitoyl tripeptide-8.
in vitro
In in vitro models, palmitoyl tripeptide-8 showed the ability to significantly inhibit IL-8 production up to 32% in UVB-irradiated keratinocytes, which was comparable to α-MSH, and also in IL-1 stimulated fibroblasts, reaching 64% inhibition which is greater that the achieved by α-MSH. In skin explants exposed to substance P, palmitoyl tripeptide-8 significantly reduced the number of dilated capillaries and the size of dilated vessels up to 30% and 51%, respectively. Edema was also reduced by 60% due to palmitoyl tripeptide-8. Palmitoyl tripeptide-8 can prevent and soothe an irritative response.
References
[1] Resende, Diana I S P et al. “Usage of Synthetic Peptides in Cosmetics for Sensitive Skin.” Pharmaceuticals (Basel, Switzerland) vol. 14,8 702. 21 Jul. 2021, doi:10.3390/ph14080702


Company Profile Introduction

Anhuyan (Hainan) Biotechnology Co., LTD, factory was founded in 2014 and has been engaged in the research and development and production of fine chemical raw materials and chemical reagents for a long time. The company has strong technical strength. Its products sell well all over the country and are exported abroad. It is deeply trusted by users and is rated as a high-tech enterprise in Hubei province. After years of development, it has now formed a variety of product series, biological buffer series; Amino acid and amino acid derivatives series; Natural cosmetic raw material Series; Chemical reagent series; Pharmaceutical and chemical raw materials and intermediates, etc. We are committed to the development of high-quality products, which have been widely used in daily chemicals, food additives, textile additives, lubricating oil, resin, pesticide, medicine and chemical industry and other industries. Products include: Condo, CAPS,TRIS, dehydrorosin, polypropylene amine hydrochloride, 5,6-dihydroxyindole, chromium acetylpyruvate, tetraacetyl ribose, phosphomolybdic acid, molybdenum acid, 4-aminoantipyrine, dihydrochalcone, dithiosulfontanol (DTT),5-isoquinoline sulfonic acid, 6-benzylaminopyrine, isopropylate, camphoroquinone, silk fibroin, docurate sodium, etc. New loyalty customers are welcome to come for consultation and purchase. Our company was renamed Hubei Yiling biotechnology LTD in 2014. It is a comprehensive high-tech modern enterprise integrating research and development, production and sales. Its sales company and research and development center are located in Guanggu biological City Medical Park, Wuhan city, Hubei Province. The company covers an area of 66279.6 sqm and has 2 production bases and 2 modern scientific research centers. The company has the international leading technical level, and has a group of professional scientific research personnel engaged in this industry. The academic leaders have a doctor's degree or above and have many years of

You may like

Recommended supplier

Product name Price   Suppliers Update time
$2.00/100kg
VIP1Y
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
2025-07-29
$100.00/1Package
VIP1Y
Huaian Banting Trading Co., Ltd.
2025-03-31
$0.00/1kg
VIP2Y
Chongqing Zhihe Biopharmaceutical Co., Ltd.
2025-03-26
$0.00/1Box
VIP1Y
American HealthyMorph LLC
2025-01-09
$0.00/1kg
VIP2Y
Fuzhou Lista Biotechnology Co.,Ltd
2024-12-26
$45.00/1kg
VIP1Y
Hebei Zhuanglai Chemical Trading Co Ltd
2024-11-14
$0.00/1kg
VIP3Y
Hebei Kingfiner Technology Development Co.Ltd
2024-06-11
$21.00/1box
Shanghai Getian Industrial Co., LTD
2024-05-09
$0.00/1kg
Shanghai Affida new material science and technology center
2024-05-06
$30.00/15mg
VIP5Y
Shanghai UCHEM Inc.
2024-04-18