
Nonapeptide-1
Price | Get Latest Price | |
Package | 1kg | 10kg |
Min. Order: | 0.001kg |
Supply Ability: | 20000000T |
Update Time: | 2025-07-28 |
Product Details
Product Name: Nonapeptide-1 | CAS No.: 158563-45-2 |
EC-No.: 000-000-0 | Min. Order: 0.001kg |
Purity: 99.99% | Supply Ability: 20000000T |
Release date: 2025/07/28 |
Chemical Properties
Density | 1.38±0.1 g/cm3(Predicted) |
solubility | soluble in water(≥0.1g/ml) |
form | Solid |
pka | 13.32±0.46(Predicted) |
color | white or off-white powder |
InChIKey | KNFLNGRLKALWRF-LDXSYGEZSA-N |
Usage And Synthesis
Description
Nonapeptide-1 is a skin lightening peptide, derived from the melanocyte stimulating hormone (MSH). It prevents the activity of tyrosine in the melanocytes, melanin synthesis inhibition and helps to even out your skin tone by lessening hyper-pigmentation. This process reduces the formation of unwanted pigmentation, allowing for the control over skin tone and brown spots.
Uses
A skin whitening nonapeptide. It can be applied to various kinds of whitening or spot corrective products.
Application
skin radiance, skin Lightening-whitening, anti-dark spot
Definition
Nonapeptide-1 is one skin whitening nonapeptide. It can be applied to various kinds of whitening or spot corrective products.
Benefits
Nonapeptide-1inhibits melanin production originally induced bya-MSH.Whitening, spot-removing as well as preventing hyperpigmentation.Its recommended dosage in skin care products is 0.5~3%.
Biological Functions
1. Inhibit melanin synthesis by interfering with the action of tyrosinase in melanocytes. Reduce hyperpigmentation and lighten darker areas that have been damaged by the sun and certain diseases.2. Interfer with melanocyte stimulating hormone (MSH). MSH increases during pregnancy, as a result of certain medical conditions (e.g. diabetes, Addison’s disease), and as a result of excessive sun exposure.3. Nonapeptide-1, at a concentration of 200 ug/mL, is capable of fully inhibiting the synthesis of melanin in fungi.4. At 100 micromolar concentration, nonapeptide-1 can inhibit 25-35% of tyrosinase activity in animal models and can reduce the melanin content of melanocytes by 27-43%
Biotechnological Applications
Nonapeptide-1 acetate salt, a peptide hormone, is a potent α-Melanocyte-stimulating hormone (α-MSH) antagonist, with an IC50 of 11 nM. Reduces synthesis of melanin and helps decrease skin pigmentation to a substantial degree[1].
Side effects
May cause drowsiness, dizziness, hypotension, or a headache as side-effects when using Nonapeptide-1 Topical medicine. Patients not drink alcohol with medicines as alcohol intensifies drowsiness side-effects.
storage
Common storage 2-8℃, long time storage -20℃.
Company Profile Introduction
Anhuyan (Hainan) Biotechnology Co., LTD, factory was founded in 2014 and has been engaged in the research and development and production of fine chemical raw materials and chemical reagents for a long time. The company has strong technical strength. Its products sell well all over the country and are exported abroad. It is deeply trusted by users and is rated as a high-tech enterprise in Hubei province.
After years of development, it has now formed a variety of product series, biological buffer series; Amino acid and amino acid derivatives series; Natural cosmetic raw material Series; Chemical reagent series; Pharmaceutical and chemical raw materials and intermediates, etc. We are committed to the development of high-quality products, which have been widely used in daily chemicals, food additives, textile additives, lubricating oil, resin, pesticide, medicine and chemical industry and other industries. Products include: Condo, CAPS,TRIS, dehydrorosin, polypropylene amine hydrochloride, 5,6-dihydroxyindole, chromium acetylpyruvate, tetraacetyl ribose, phosphomolybdic acid, molybdenum acid, 4-aminoantipyrine, dihydrochalcone, dithiosulfontanol (DTT),5-isoquinoline sulfonic acid, 6-benzylaminopyrine, isopropylate, camphoroquinone, silk fibroin, docurate sodium, etc. New loyalty customers are welcome to come for consultation and purchase.
Our company was renamed Hubei Yiling biotechnology LTD in 2014. It is a comprehensive high-tech modern enterprise integrating research and development, production and sales. Its sales company and research and development center are located in Guanggu biological City Medical Park, Wuhan city, Hubei Province. The company covers an area of 66279.6 sqm and has 2 production bases and 2 modern scientific research centers. The company has the international leading technical level, and has a group of professional scientific research personnel engaged in this industry. The academic leaders have a doctor's degree or above and have many years of
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