
Nectin-2 Protein, Mouse, Recombinant (hFc) NEW
Price | $3060 |
Package | 1mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2025-07-22 |
Product Details
Product Name: Nectin-2 Protein, Mouse, Recombinant (hFc) | Supply Ability: 10g |
Release date: 2025/07/22 |
Product Introduction
Bioactivity
Name | Nectin-2 Protein, Mouse, Recombinant (hFc) |
Description | CD112 is a type I transmembrane glycoprotein belonging to the Immunoglobulin superfamily. It comprises one Ig-like V-type domain and two Ig-like C2-type domains in the extracellular region. The V domain is believed to mediate nectin binding to its ligands. Nectin2 is known to bind the pseudorabies virus, and herpes simplex virus2 (HSV2), involving in cell to cell spreading of these viruses. It does not bind poliovirus. As a homophilic adhesion molecule, CD112 is found concentrated in adherens junctions, and exists on neurons, endothelial cells,epithelial cells and fibroblasts. CD112 has been identified as the ligand for DNAM-1 (CD226), and the interaction of CD226/CD112 mediates cytotoxicity and cytokine secretion by T and NK cells. The costimulatory responses may be a critical component in allergic reactions and may therefore become targets for anti-allergic therapy. |
Storage | Shipping with blue ice/Shipping at ambient temperature. |
Keywords | PVRL-2 | PVRL 2 | PRR-2 | PRR 2 | CD-112 | CD 112 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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