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Postion:Product Catalog >Naproxen etemesil
Naproxen etemesil
  • Naproxen etemesil

Naproxen etemesil NEW

Price $854 $1110 $1610
Package 25mg 50mg 100mg
Min. Order:
Supply Ability: 10g
Update Time: 2025-07-17

Product Details

Product Name: Naproxen etemesil CAS No.: 385800-16-8
Supply Ability: 10g Release date: 2025/07/17

Product Introduction

Bioactivity

NameNaproxen etemesil
DescriptionNaproxen is a COX-1 and COX-2 inhibitor (IC50s: 8.72 and 5.15 μM, respectively in cell assay). Naproxen etemesil is a lipophilic and non-acidic prodrug of naproxen. It is hydrolyzed to pharmacologically active Naproxen once absorbed.
In vitroNaproxen is a well known nonsteroidal anti-inflammatory drug. Naproxen is an approximately equipotent inhibitor of COX-1 and COX-2 in intact cells (IC50s: 2.2 μg/mL and 1.3 μg/mL, respectively)[1].
In vivoNaproxen is shown to inhibit the time-courses of pain, fever, and PGE2 with similar potencies (IC50=27, 40, 13 μM). Naproxen exerts an anti-inflammatory and antifibrotic effect in the mouse model of bleomycin-induced lung fibrosis. Naproxen also downregulates TGF-β levels and Smad3/4 complex formation [2][3].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
KeywordsNaproxen etemesil | MX-1094 | MX1094 | LT-NS-001 | LT-NS001 | COX-2 | COX-1
Inhibitors RelatedTheophylline monohydrate | Acefylline | Roflumilast | Theobromine | Apremilast | Isoprenaline hydrochloride | Indomethacin | Icariin | Theophylline | Vardenafil hydrochloride | Sildenafil citrate | Doxofylline

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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