
Moslosooflavone NEW
Price | $71 | $172 | $259 |
Package | 1mg | 5mg | 10mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2025-07-24 |
Product Details
Product Name: Moslosooflavone | CAS No.: 3570-62-5 |
Purity: 98.00% | Supply Ability: 10g |
Release date: 2025/07/24 |
Product Introduction
Bioactivity
Name | Moslosooflavone |
Description | Moslosooflavone (5-hydroxy-7,8-dimethoxyflavone) has anti-hypoxia activity, it can significantly prolong the survival time of hypoxic mice. 5-hydroxy-7,8-dimethoxyflavone significantly inhibits the transcriptional activity of NF-kappaB in LPS/IFN-gamma stimulated RAW 264.7 macrophages. |
Animal Research | The chemical constituents, isolated and purified by column chromatography from Saussurea invo lucrata, were identified by several spectroscopic methods. The anti-hypoxic activities of these compounds were examined using the normobaric hypoxic model of mice[2]. |
In vitro | 5-hydroxy-7,8-dimethoxyflavone significantly decreased TNF-alpha, IL-6, macrophage inflammatory protein-2 (MIP-2), and nitric oxide (NO) secretions from LPS/IFN-gamma stimulated RAW 264.7 cells[1]. |
In vivo | 5-hydroxy-7,8-dimethoxyflavone can significantly prolong the survival time of hypoxic mice[2]. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Solubility Information | DMSO : 10 mg/mL (33.52 mM), Sonication is recommended. |
Keywords | ReactiveOxygenSpecies | Reactive Oxygen Species | NF-κB | NFκB | NF-kB | NFkB | Moslosooflavone | Inhibitor | inhibit | flavonoid | anti-inflammatory | anti-hypoxia |
Inhibitors Related | Cysteamine hydrochloride | Imeglimin hydrochloride | Naringin dihydrochalcone | L-Ascorbic acid | Hesperidin | Glucosamine | N,N-Dimethylacetamide | L-Ascorbic acid sodium salt | Sodium 2-oxopropanoate | Naringenin | Uric Acid | Diallyl disulfide |
Related Compound Libraries | Anti-Tumor Natural Product Library | Flavonoid Natural Product Library | Bioactive Compound Library | Traditional Chinese Medicine Monomer Library | Anti-Neurodegenerative Disease Compound Library | Natural Product Library | Anti-Inflammatory Traditional Chinese Medicine Compound Library | Natural Product Library for HTS | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | Heat-Clearing and Detoxifying Traditional Chinese Medicine Compound Library | Ancient Chinese Classical Formulas Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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