Product Details
| Product Name:
Moscatin |
CAS No.:
108335-06-4 |
| Purity:
99.89% |
Supply Ability:
10g |
| Release date:
2025/05/26 |
Product Introduction
Bioactivity
| Name | Moscatin |
| Description | Moscatin (Plicatol, 4-methoxyphenanthrene-2,5-diol) is a diphenyl derivative that can be extracted from Dendrobium nobile Lindl. It inhibits arachidonic acid-induced platelet aggregation, and is able to inhibit Candida albicans virulence and growth by down-regulating the expression of genes such as ERG, HSP, and ALS. |
| In vitro | Moscatin inhibits washed rabbit platelet aggregation in a concentration-dependent manner, showing complete inhibition of AA- and collagen-induced aggregation at 100?μg/mL. Moscatin IC?? against AA-induced aggregation is 37.2?μM, likely by interfering with thromboxane A? formation [1]. |
| In vivo | In mouse infection models (systemic and OPC), moscatin injection (20?μg/mL, 200?μL) significantly reduced the pathogenicity of Candida albicans SC5314 [2]. Moscatin restored gut microbiota balance in Candida albicans-infected mice, increasing beneficial bacteria levels and reducing fungal burden [2]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Keywords | Moscatin |
| Inhibitors Related | Ethoxyquin | Quinine | 3',4'-Dihydroxyacetophenone | Tamoxifen | 4(3H)-Quinazolinone | Carbasalate calcium | Elesclomol | Teprenone | Rifabutin | Palmitic acid | Paeoniflorin | 17-AEP-GA |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
-
-
-
CAS:38451-63-7
$90.00 / 1mg
Recommended supplier
| Product name |
Price |
|
Suppliers |
Update time |
|
|
$9.80/1KG |
VIP6Y
|
Career Henan Chemical Co
|
2020-02-06 |
United States