Product Details
Product Name:
MK-8325 |
CAS No.:
1334314-19-0 |
Purity:
100% |
Supply Ability:
10g |
Release date:
2025/07/15 |
Product Introduction
Bioactivity
Name | MK-8325 |
Description | MK-8325 is a potent and orally available HCV NS5A inhibitor with replicative activity against a wide range of genotypes.MK-8325 has demonstrated bioavailability in in vitro and in vivo assays and has a favorable overall ADME profile. |
In vitro | MK-8325 (7 μM) demonstrates no cell toxicity with a CC50 > 25 mM against Huh-7 replicon cells in a standard MTS assay.[1] |
In vivo | In vivo assays showed MK-8325 to be orally bioavailable with pharmacokinetics suitable for once-daily dosing in patients and good overall ADME profiles.[1] |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : 9.16 mg/mL (10 mM), Sonication is recommended.
|
Keywords | MK-8325 | HCVProtease | HCV Protease | HCV NS5A |
Inhibitors Related | EIDD-1931 | AG-1478 | Methyl 2-amino-5-bromobenzoate | RO8191 | Ribavirin | Sofosbuvir | Deferiprone | Ombitasvir | Artemisinin | HCV-IN-29 | Honokiol | Resiquimod |
Related Compound Libraries | Failed Clinical Trials Compound Library | Bioactive Compound Library | Drug Repurposing Compound Library | Anti-Viral Compound Library | Inhibitor Library | Orally Active Compound Library | Clinical Compound Library | Bioactive Compounds Library Max | Fluorochemical Library | Anti-Infection Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
Product name |
Price |
|
Suppliers |
Update time |
|
$0.00/10g |
VIP1Y
|
Wuhan Kejiefeng Trading Co.,Ltd
|
2025-05-07 |
|
$270.00/100g |
VIP3Y
|
Anko Intermational Trade Limited
|
2023-05-22 |
|
$5.00/1Box |
VIP1Y
|
Hebei Jiafan Trading Company Limited
|
2025-01-08 |