
Maytansinoid B NEW
Price | Get Latest Price | |
Package | 5mg | 50mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2025-07-16 |
Product Details
Product Name: Maytansinoid B | CAS No.: 1628543-40-7 |
Supply Ability: 10g | Release date: 2025/07/16 |
Product Introduction
Bioactivity
Name | Maytansinoid B |
Description | Maytansinoid B, an ADC cytotoxin, conjugates with antibodies to create antibody-drug conjugates (ADCs). This antimitotic agent binds to tubulin, inhibiting microtubule assembly, and induces G2/M arrest in the cell cycle, leading to apoptosis [1] [2]. |
In vitro | Maytansinoid displays cytotoxic activity in the range of 10-90 pM against several tumor cell lines, including lymphoma [1]. When conjugated with an anti-CD9 antibody, it forms SAR3419, which targets B-cell malignancies [1]. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Keywords | ADCCytotoxin | ADC Cytotoxin |
Inhibitors Related | Methotrexate | Mertansine | Doxorubicin hydrochloride | Daunorubicin hydrochloride | Exatecan | Methotrexate disodium | Camptothecin | Dexamethasone | Fluticasone (propionate) | Paclitaxel | 17-AEP-GA | Exatecan Mesylate |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries, 10000+ Noval Small Molecucles,16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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