LY339434 HCl NEW
| Price | $195 | $430 | $636 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-06-18 |
Product Details
| Product Name: LY339434 HCl | Purity: 99.68% |
| Supply Ability: 10g | Release date: 2025/06/18 |
Product Introduction
Bioactivity
| Name | LY339434 HCl |
| Description | LY339434 HCl is a low affinity GluR5 erythrocyte receptor agonist.LY339434 HCl causes rapid neuronal death primarily by affecting N-methyl-D-aspartate (NMDA) receptors. |
| In vitro | LY339434 HCl (1-1000 μM) caused a concentration-dependent decrease in cell viability (EC(50)=11.4+/-1.2 μM). Labeling with nucleic acid binding dyes revealed that LY339434 HCl induced a few apoptotic-like characteristics. These findings indicate that in cultured murine cortical neurons, LY339434 HCl acts predominantly through N-methyl-D-aspartate (NMDA) receptors rather than GluR5 to affect neuronal death that is rapid and involves predominantly necrosis rather than morphological apoptosis.[1] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 50 mg/mL (142.93 mM), Sonication is recommended. |
| Keywords | NMDA receptor | mGluR5 | LY339434 HCl |
| Inhibitors Related | Mephenesin | Urethane | Decanoic Acid | Halothane | Evans blue | L-Glutamine | Direct Blue 1 | L-Glutamic acid monosodium salt | Riluzole | Piracetam | O-Phospho-L-serine | Procaine hydrochloride |
| Related Compound Libraries | Anti-Neurodegenerative Disease Compound Library | Bioactive Compound Library | Pain-Related Compound Library | Neuronal Signaling Compound Library | Membrane Protein-targeted Compound Library | Glutamine Metabolism Compound Library | Neurotransmitter Receptor Compound Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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