Product Details
Product Name:
LY2955303 |
CAS No.:
1433497-19-8 |
Purity:
99.85% |
Supply Ability:
10g |
Release date:
2025/05/12 |
Product Introduction
Bioactivity
Name | LY2955303 |
Description | LY2955303 is an effective and selective antagonist of retinoic acid receptor gamma (RARγ, Ki = 1.09 nM). |
In vitro | The functional Ki for RARγ is 7.1±4.9 nM. The binding Kis of LY2955303 for RARα, RARβ, and RARγ are >1700, >2980, and 1.09 nM, respectively[1]. |
In vivo | A single dose of LY2955303(oral) showed a dose-response effect in rats with different weight-bearing reductions with an ED50 of 0.72 mg/kg[1]. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : 25 mg/mL (43.20 mM), Sonication and heating are recommended.
|
Keywords | RetinoidReceptor | Retinoid X receptors | Retinoid Receptor | Retinoic acid receptors | RARγ | RAR/RXR | LY-2955303 | LY2955303 | LY 2955303 | Inhibitor | inhibit | Autophagy |
Inhibitors Related | Isotretinoin | Adapalene | Oxybenzone | MSU-42011 | Tazarotene | Etodolac | ER 50891 | Acitretin | Tamibarotene | Bexarotene | TTNPB | K-8012 |
Related Compound Libraries | Nuclear Receptor Compound Library | Bioactive Compound Library | Cancer Cell Differentiation Compound Library | Inhibitor Library | Metabolism Compound Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
Product name |
Price |
|
Suppliers |
Update time |
|
$/ |
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Anhui Ruihan Technology Co., Ltd
|
2023-08-21 |