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Postion:Product Catalog >Lapatinib Impurity 6
Lapatinib Impurity 6
  • Lapatinib Impurity 6
  • Lapatinib Impurity 6
  • Lapatinib Impurity 6
  • Lapatinib Impurity 6
  • Lapatinib Impurity 6

Lapatinib Impurity 6 NEW

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Package 10mg 50mg 100mg
Min. Order: 10mg
Supply Ability: 1000
Update Time: 2025-07-31

Product Details

Product Name: Lapatinib Impurity 6 CAS No.: 746591-42-4
Min. Order: 10mg Purity: 99%+ HPLC
Supply Ability: 1000 Release date: 2025/07/31
Molecular formula: C26H18FN3O3

Lapatinib Impurity 6;746591-42-4

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WhatsAPP: +86 17386083646
E-mail: anna@molcoo.com

  • Product Number: L079006
    English Name: Lapatinib Impurity 6
    English Alias: 5-(4-((4-((3-fluorobenzyl)oxy)phenyl)amino)quinazolin-6-yl)furan-2-carbaldehyde
    CAS Number: 746591-42-4
    Molecular Formula: C??H??FN?O?
    Molecular Weight: 439.44

  • Product Advantages: Lapatinib Impurity 6 has high purity and excellent chemical stability. Its structure is confirmed by precise analytical methods such as nuclear magnetic resonance and mass spectrometry, and it remains stable and uniform under different experimental conditions. As a reference substance, its precise purity control and stable physical-chemical properties ensure the accuracy and repeatability of Lapatinib impurity detection results, providing a reliable basis for pharmaceutical quality research and quality control.

  • Application Fields:

  • Quality Control: Used as an impurity reference standard for the development and validation of detection methods for Lapatinib bulk drugs and formulations, ensuring that the sensitivity and specificity of detection methods meet pharmaceutical quality standard requirements.

  • Process Optimization: Monitors the content of this impurity during drug production, and assists in optimizing the synthesis process by analyzing its formation pathway to reduce impurity generation and improve product quality.

  • Stability Studies: Analyzes the change trend of this impurity under different storage conditions in drug stability tests, providing data support for determining the shelf life and storage conditions of drugs.


  • Background Description: Lapatinib is a targeted drug for the treatment of HER2-positive breast cancer. In its research, development, production and quality control, impurity research is a key link to ensure drug safety and effectiveness. As a related impurity of Lapatinib, Lapatinib Impurity 6 may originate from side reactions or intermediate residues in the synthesis process. Excessive content may affect drug efficacy or bring safety risks. Therefore, the study of this impurity is an important part of the Lapatinib quality evaluation system.

  • Research Status: Currently, research on Lapatinib Impurity 6 mainly focuses on detection technology and impurity generation mechanisms. In terms of detection technology, advanced methods such as Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry (UPLC-MS/MS) have been developed to achieve trace detection. By simulating the synthesis reaction and storage environment, it is found that the formation of this impurity is related to the by-products of fluorobenzylation reaction. Optimizing the reaction solvent (such as replacing methanol with dimethyl sulfoxide) can reduce its generation. In addition, the study on the effect of this impurity on the efficacy and safety of Lapatinib is still being further explored.

NOTE!

We can also customize related analogues and modified peptides including HPLC, MS, 1H-NMR, MS, HPLC, IR, UV, COA, MSDS.
This product is intended for laboratory use only!

WhatsAPP: +86 17386083646
E-mail: anna@molcoo.com


NEW IN STOCK!

The Molcoo Laboratory added drug impurity reference standards, including Baricitinib, Piperazine, Benzylpenicillin, Tranilast and multiple N-Nitroso drug impurities! Now available for immediate delivery! 




Company Profile Introduction

1. Drug standards and drug impurity reference substances: provide more than 20,000 kinds of spot impurity reference substances, with sufficient supply and same-day delivery. We have a professional R&D team and comprehensive quality control testing to ensure product quality and reliability. 2. Customized synthesis of impurities and new molecules: Quickly respond to the customized needs of CDE impurities, stably supply impurities that have established quality standards, and provide customized synthesis services for new compounds in the research and development of innovative drugs. 3. Preparation and separation of unknown impurities: With a professional impurity preparation and separation technical team and SFC preparation and separation instruments, we can solve the problems of impurity preparation in complex projects. 4. Process development of new drug intermediates: provide the supply of new drugs and new molecular impurities, process optimization services, as well as the screening and impurity analysis of commercialization routes. 5. Peptide synthesis: Provide customized peptide synthesis services, and cover all kinds of degradation impurities and process impurities generated in the research and development of peptide drugs. At the same time, it provides comprehensive structural confirmation data and customized testing services.

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