PRODUCT INFORMATION

Names

Name	L-gulono-1,4-lactone
Synonym	More Synonyms

 L-Gulonic g-lactone Biological Activity

Description	L-Gulono-1,4-lactone is a substrate of L-gulono-1,4-lactone oxidoreductase, which catalyzes the last step of the biosynthesis of L-ascorbic (Vatamin) C. In other words, L-Gulono-1,4-lactone is a direct precursor of vitamin C in animals, in plants and in some protists.
Related Catalog	Research Areas >> Metabolic Disease Natural Products >> Others
Target	Human Endogenous Metabolite
References	[1]. Wolucka BA, et al. Mycobacterium tuberculosis possesses a functional enzyme for the synthesis of vitamin C, L-gulono-1,4-lactone dehydrogenase. FEBS J. 2006 Oct;273(19):4435-45. Epub 2006 Sep 5.

 Chemical & Physical Properties

Density	1.8±0.1 g/cm3
Boiling Point	467.9±18.0 °C at 760 mmHg
Melting Point	187-190oC(lit.)
Molecular Formula	C6H10O6
Molecular Weight	178.140
Flash Point	201.5±14.7 °C
Exact Mass	178.047745
PSA	107.22000
LogP	-3.15
Vapour Pressure	0.0±2.6 mmHg at 25°C
Index of Refraction	1.625
Storage condition	2~8°C

 MSDS

L-Gulonic g-lactone MSDS(Chinese)

 Safety Information

Hazard Codes	Xi
Safety Phrases	22-24/25
WGK Germany	3
HS Code	2932209090

 Synthetic Route

Previous 1/2 Next

Ascorbic acid CAS#:50-81-7 ~96% L-Gulonic g-lactone CAS#:1128-23-0

Literature: Andrews; Crawford; Bacon Journal of Organic Chemistry, 1981 , vol. 46, # 14 p. 2976 - 2977

D-gluconic acid CAS#:157663-13-3 ~% L-Gulonic g-lactone CAS#:1128-23-0

Literature: Journal of the American Chemical Society, , vol. 67, p. 1713 Recueil des Travaux Chimiques des Pays-Bas, , vol. 74, p. 1365,1367

N/A CAS#:945622-66-2 ~% L-Gulonic g-lactone CAS#:1128-23-0

Literature: Synlett, , # 8 p. 1247 - 1250

 Precursor & DownStream

Precursor  4
CAS#:50-81-7 Ascorbic acid  CAS#:367523-78-2 2,3,4,6-trimeth...  CAS#:389-36-6 D-(tetrahydro-2...  CAS#:87-73-0 Saccharic acid
DownStream  9	Previous 1/3 Next
CAS#:50-81-7 Ascorbic acid  CAS#:609-06-3 L-Xylose  CAS#:73285-50-4 1-Deoxynojirimy...  CAS#:112837-17-9 (R)-(+)-5-(Hydr...

 Customs

HS Code	2932209090
Summary	2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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