L-2-Hydroxyglutaric acid NEW
| Price | Get Latest Price | ||
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-07-17 |
Product Details
| Product Name: L-2-Hydroxyglutaric acid | CAS No.: 13095-48-2 |
| Supply Ability: 10g | Release date: 2025/07/17 |
Product Introduction
Bioactivity
| Name | L-2-Hydroxyglutaric acid |
| Description | L-2-Hydroxyglutaric acid (L-2-HG) is a compartmentalized metabolite and a substrate for L-2-hydroxyglutarate dehydrogenase (L2HGDH). It inhibits histone demethylases and increases the expression of ATF4 and its target genes by activating the mTOR pathway. L-2-Hydroxyglutaric acid mediates the mTOR-ATF4 signaling pathway and can be used in biosensor research. |
| In vitro | L-2-Hydroxyglutaric acid exhibits potent inhibition of 2-oxoglutarate (2-OG)-dependent dioxygenases (2OGDs), including Ten Eleven Translocation (TET) enzymes. [1] L-2-Hydroxyglutaric acid was able to effectively inhibit mitochondrial creatine kinase (Mi-CK) activity with a Km value of 2.52 mM and a Ki value of 11.13 mM. [2] |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | L-2-Hydroxyglutaric acid | L2Hydroxyglutaric acid | L 2 Hydroxyglutaric acid | Human Endogenous Metabolite | 2-Hydroxyglutaric acid |
| Inhibitors Related | Sucrose | Daidzein | Guanidine hydrochloride | Fumaric acid | Ferulic Acid | L-Methionine | Oleamide | Glycerol | Thymidine | Naringin | L-Ascorbic acid sodium salt | 3-Indoleacetic acid |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
Recommended supplier
| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $45.00/10mg |
VIP5Y
|
TargetMol Chemicals Inc.
|
2025-07-31 | |
| $0.00/1kg |
VIP3Y
|
Henan Aochuang Chemical Co.,Ltd.
|
2022-09-28 | |
| $99.00/5kg |
VIP1Y
|
HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
|
2024-08-12 |
United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
INQUIRY