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Postion:Product Catalog >KEA1-97
KEA1-97
  • KEA1-97

KEA1-97 NEW

Price $41 $86 $137
Package 10mg 25mg 50mg
Min. Order:
Supply Ability: 10g
Update Time: 2025-05-28

Product Details

Product Name: KEA1-97 CAS No.: 2138882-71-8
Purity: 98.7% Supply Ability: 10g
Release date: 2025/05/28

Product Introduction

Bioactivity

NameKEA1-97
DescriptionKea1-97 is a selective disruptor of interaction between thioredoxin and caspase-3 (IC50 = 10 μ M). Kea1-97 destroys the interaction between thioredoxin and caspase 3 and activates caspases without affecting the activity of thioredoxin.
In vitroKEA1-97 (10 μM, 48h) impaired 231MFP cell survival and proliferation and does not affect viability in MCF10A cells.
In vivoKEA1–97 treatment (5 mg/kg ip once per day) was initiated 16 days after the initiation of 231MFP tumor xenografts in immune-deficient SCID mice.
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 90 mg/mL (268.53 mM), Sonication is recommended.
KeywordsThiordoxine | Selective | Proliferation | KEA1-97 | KEA-1-97 | KEA197 | KEA1 97 | Inhibitor | inhibit | DCTalkyne | Caspase-3 | Caspase | Apoptotic | Apoptosis | 231MFP
Inhibitors RelatedStavudine | 5-Fluorouracil | Flubendazole | Cysteamine hydrochloride | Myricetin | Dextran sulfate sodium salt (MW 4500-5500) | Sodium 4-phenylbutyrate | L-Ascorbic acid | L-Glutamic acid | Tributyrin | L-Ascorbic acid sodium salt | Alginic acid
Related Compound LibrariesApoptosis Compound Library | Anti-Neurodegenerative Disease Compound Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Protease Inhibitor Library | Pyroptosis Compound Library | NO PAINS Compound Library | PPI Inhibitor Library | Bioactive Compounds Library Max | Fluorochemical Library | Anti-Cancer Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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