Istaroxime NEW
| Price | $2420 | $3180 | $4300 |
| Package | 25mg | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-07-19 |
Product Details
| Product Name: Istaroxime | CAS No.: 203737-93-3 |
| Supply Ability: 10g | Release date: 2025/07/19 |
Product Introduction
Bioactivity
| Name | Istaroxime |
| Description | Istaroxime is an effective inhibitor of Na+, K+-ATPase (IC50: 0.11 μM). |
| In vitro | Istaroxime inhibits the Na+/K+-ATPase activity from the dog kidney (IC50: 0.43 ± 0.15 μM). Istaroxime acting as a positive inotropic compound through the inhibition of the Na+, K+-ATPase[2]. Inhibition of Na+/K+-ATPase activity in preparations from guinea pig kidney yielded potencies of 8.5 μM for PST2744[3]. |
| In vivo | Istaroxime (PST2744) causes a progressive to enhance in +dP/dtmax throughout the infusion. That reaches 80% (ED80) at the cumulative dose of 1.89±0.37 mg/kg and a peak of 140±3.5% at the dose (EDmax) of 4.88±0.6 mg/kg[3]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | PST-2744 | PST 2744 | Na+,K+-ATPase | Istaroxime |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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