Iloprost NEW
| Price | Get Latest Price | |
| Package | 1mg | 5mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-07-26 |
Product Details
| Product Name: Iloprost | CAS No.: 78919-13-8 |
| Supply Ability: 10g | Release date: 2025/07/26 |
Product Introduction
Bioactivity
| Name | Iloprost |
| Description | Iloprost (Ciloprost) is a stabilized synthetic analog of prostaglandin I2, an inhibitor of platelet aggregation and vasodilation, used in the study of cardiovascular disease. |
| In vitro | Iloprost is a PGI2 analog that affects the maturation and developmental competence of bovine oocytes. 0.5 μM Iloprost treatment for 22-24 hours increased the blastocyst rate and the proportion of expanded blastocysts in bovine embryos, increased the maturation rate of bovine oocytes and the rate of cumulus expansion, and increased mRNA expression of genes associated with cumulus expansion. [1] Iloprost reduces the occurrence of apoptosis in COC cells and promotes an anti-apoptotic balance in the transcription of apoptosis-related genes (BAX and BCL2). [1] |
| In vivo | 0.3 mg/kg/min Iloprost, administered intravenously by minipump for 33 days, showed significant anti-metastatic activity in a rat model of spontaneous metastatic tumors.[3] 0.2 mg/kg/day Iloprost, administered intravenously for 10 days, attenuated the effects of hyperoxia and reduced inflammation in the lungs of neonatal mice, where cyclooxygenase-2 (COX-2/PTGS2) mediated hyperoxia-induced injury.[2] |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 80 mg/mL (221.92 mM), Sonication is recommended. |
| Keywords | ZK-36374 | ProstaglandinReceptor | Prostaglandin Receptor | Iloprost | EndogenousMetabolite | Endogenous Metabolite |
| Inhibitors Related | Sucrose | Cysteamine hydrochloride | Acetaminophen | Daidzein | Guanidine hydrochloride | Fumaric acid | Ferulic Acid | Formamide | Glycerol | Thymidine | Naringin | 3-Indoleacetic acid |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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