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Postion:Product Catalog >Biochemical Engineering>Inhibitors>Metabolism>IDO inhibitors>IDO-IN-7
IDO-IN-7
  • IDO-IN-7

IDO-IN-7 NEW

Price $38 $58 $95
Package 2mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2025-07-15

Product Details

Product Name: IDO-IN-7 CAS No.: 1402836-58-1
Purity: 99.87% Supply Ability: 10g
Release date: 2025/07/15

Product Introduction

Bioactivity

NameIDO-IN-7
DescriptionIDO-IN-7 (NLG-919 analogue) is a potent inhibitor of the IDO (indoleamine-(2, 3)-dioxygenase) pathway.
In vitroIn mice bearing B16F10 tumors, NLG919 significantly enhanced the antitumor response of pmel-1 resting cells to homologous hgp100 peptide and CpG-1826.
In vivoNLG919 effectively blocks the IDO-induced suppression of T-cell responses, restoring T-cell activity (ED50=80 nM). In mouse dendritic cells (DCs) expressing IDO from tumor lymph nodes (ED50=120 nM), NLG919 abolishes the IDO-induced inhibition of antigen-specific T-cells (OT-1).
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationEthanol : 26 mg/mL (92.07 mM), Sonication is recommended.
DMSO : 45 mg/mL (159.36 mM), Sonication is recommended.
H2O : < 1 mg/mL (insoluble or slightly soluble)
KeywordsNLG919 analogue | NLG-919 | NLG 919 | Navoximod analogue | Indoleamine2,3Dioxygenase(IDO) | Indoleamine2,3Dioxygenase | Indoleamine 2,3-Dioxygenase (IDO) | Indoleamine 2,3Dioxygenase (IDO) | Indoleamine 2,3-Dioxygenase | IDO-IN-7 | IDOIN7 | IDO IN 7 | IDO | GDC-0919 analogue | GDC0919 | GDC 0919
Inhibitors RelatedPalmatine chloride | IDO-IN-1 | GNF-PF-3777 | Coptisine chloride | Necrostatin-1 | Coptisine sulfate | Indoximod | Palmatine | IDO inhibitor 1 | Epacadostat | IDO5L | IDO-IN-12
Related Compound LibrariesTarget-Focused Phenotypic Screening Library | Bioactive Compound Library | ReFRAME Related Library | Anti-Cancer Metabolism Compound Library | Anti-Cancer Clinical Compound Library | Drug Repurposing Compound Library | Inhibitor Library | Bioactive Compounds Library Max | Anti-Metabolism Disease Compound Library | Human Metabolite Library | Anti-Cancer Drug Library | Anti-Cancer Active Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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