HX 531 NEW
| Price | $39 | $68 | $122 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-05-02 |
Product Details
| Product Name: HX 531 | CAS No.: 188844-34-0 |
| Purity: 99.43% | Supply Ability: 10g |
| Release date: 2025/05/02 |
Product Introduction
Bioactivity
| Name | HX 531 |
| Description | HX 531 is a RXR antagonist (IC50 of 18 nM). HX 531 prevents HF diet-induced obesity, insulin resistance, and diabetes by reducing tissue TG content in white adipose tissue (WAT), skeletal muscle, and liver in mice. |
| In vivo | METHODS: HX531 (100 mg/kg, oral) was administered to mice, and the maximum plasma concentration (Cmax), time required to reach maximum concentration (Tmax), area under the plasma concentration-time curve (AUC), and elimination half-life (t1/2) were measured by HPLC and gas chromatography. RESULTS In mice, they were 4.1 μg/mL, 1.5 hours, 19.3 μg h/mL, and 1.9 hours, respectively. [2] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 3 mg/mL (6.2 mM), Sonication is recommended. |
| Keywords | RXR | RetinoidReceptor | Retinoid X receptors | Retinoid Receptor | Retinoic acid receptors | RAR/RXR | Inhibitor | inhibit | HX-531 | HX531 | HX 531 |
| Inhibitors Related | Isotretinoin | Adapalene | Oxybenzone | MSU-42011 | Tazarotene | Etodolac | ER 50891 | Acitretin | Tamibarotene | Bexarotene | TTNPB | K-8012 |
| Related Compound Libraries | Nuclear Receptor Compound Library | Bioactive Compound Library | Cancer Cell Differentiation Compound Library | Inhibitor Library | Metabolism Compound Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
Recommended supplier
| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $2500.00/100mg |
VIP2Y
|
TargetMol Chemicals Inc.
|
2025-04-30 | |
| $0.00/1kg |
VIP2Y
|
Watson Biotechnology Co.,Ltd
|
2025-07-11 | |
| $60.00/1kg |
Hebei Zhuanglai Chemical Trading Co.,Ltd
|
2024-05-15 |
United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
INQUIRY