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Postion:Product Catalog >hSMG-1 inhibitor 11j
hSMG-1 inhibitor 11j
  • hSMG-1 inhibitor 11j

hSMG-1 inhibitor 11j NEW

Price $163 $243 $413
Package 1mg 2mg 5mg
Min. Order:
Supply Ability: 10g
Update Time: 2025-06-24

Product Details

Product Name: hSMG-1 inhibitor 11j CAS No.: 1402452-15-6
Purity: 99.65% Supply Ability: 10g
Release date: 2025/06/24

Product Introduction

Bioactivity

NamehSMG-1 inhibitor 11j
DescriptionhSMG-1 inhibitor 11j is a pyrimidine derivative. hSMG-1 inhibitor 11j is a potent and selective inhibitor of hSMG-1, IC50 = 0.11 nM. hSMG-1 inhibitor 11j exhibits >455-fold selectivity for hSMG-1 over mTOR (IC50=50 nM), PI3Kα/γ (IC50=92/60 nM) and CDK1/CDK2 (IC50=32/7.1 μM). hSMG-1 inhibitor 11j can be used for the research of cancer.
In vitrohSMG-1 inhibitor 11j (0.3-3 μM; 6 h) significantly reduces UPF1 phosphorylation at 0.3 μM and eliminates it at 1 μM in MDA 361 cells. It also inhibits MDA468 cell proliferation with an IC50 of 75 nM [1].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility InformationDMSO : 70 mg/mL (123.7 mM), Sonication is recommended.
KeywordsPI3Kα/PI3Kγ | mTOR | hSMG-1 inhibitor 11j | hSMG1 inhibitor 11j | hSMG 1 inhibitor 11j
Inhibitors RelatedL-Leucine | Myricetin | Erucic acid | Sapanisertib | (2S,3R,4S)-4-Hydroxyisoleucine | 3-Methyladenine | Isoprenaline hydrochloride | Quercetin | Inavolisib | Quercetin Dihydrate | Apilimod | Rapamycin
Related Compound LibrariesAnti-Lung Cancer Compound Library | Bioactive Compound Library | Kinase Inhibitor Library | Hematonosis Compound Library | Anti-Breast Cancer Compound Library | Antioxidant Compound Library | Inhibitor Library | Anti-Aging Compound Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | Anti-Cancer Active Compound Library | Neuronal Differentiation Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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