HIV-1 inhibitor-47 NEW
| Price | $1520 | $1980 | $2500 |
| Package | 25mg | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-04-29 |
Product Details
| Product Name: HIV-1 inhibitor-47 | CAS No.: 137448-39-6 |
| Supply Ability: 10g | Release date: 2025/04/29 |
Product Introduction
Bioactivity
| Name | HIV-1 inhibitor-47 |
| Description | HIV-1 inhibitor-47 is a compound that effectively inhibits HIV-1 by preventing the vif-dependent degradation of human APOBEC3G. It has a notable inhibition effect, with an IC50 value of 14.33 μM. Additionally, HIV-1 inhibitor-47 is involved in the synthesis of derivatives of 1-(2-pyrimidinyl)piperazine, which have the potential to exhibit antianxiety, antidepressant, and antipsychotic effects [1] [2] [3]. |
| In vitro | APOBEC3G (A3G), a host cytidine deaminase, inhibits HIV-1 replication through its antiviral activity. Nonetheless, HIV-1 circumvents this defense by exploiting the cellular ubiquitin/proteasome degradation pathway [1]. HIV-1 inhibitor-47 targets the APOBEC3G-apolipoprotein B mRNA editing enzyme catalytic subunit 3G (human), disrupting the HIV-1 Vif-APOBEC3G interaction [2]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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