Hemopressin(rat) TFA NEW
| Price | Get Latest Price | |
| Package | 5mg | 50mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-04-28 |
Product Details
| Product Name: Hemopressin(rat) TFA | CAS No.: 1431329-47-3 |
| Supply Ability: 10g | Release date: 2025/04/28 |
Product Introduction
Bioactivity
| Name | Hemopressin(rat) TFA |
| Description | Hemopressin(rat) TFA, a nonapeptide originating from the α1-chain of hemoglobin, was first isolated from rat brain homogenates. It acts as an orally active, selective, and inverse agonist of the CB1 cannabinoid receptors and demonstrates antinociceptive effects in models of inflammatory pain [1] [2]. |
| In vivo | Hemopressin(rat) TFA induces hypotension in anesthetized rats, undergoing metabolism by endopeptidase 24.15 (EP24.15), neurolysin (EP24.16), and angiotensin-converting enzyme (ACE) [1]. When administered orally, it mitigates mechanical hyperalgesia in CCI-rats for up to 6 hours. Additionally, treatment with Hemopressin(rat) TFA reduces Egr-1 immunoreactivity (Egr-1Ir) in the spinal cord's superficial dorsal horn of CCI rats [2]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
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TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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