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Postion:Product Catalog >GW-803430
GW-803430
  • GW-803430

GW-803430 NEW

Price $559 $779 $1050
Package 25mg 50mg 100mg
Min. Order:
Supply Ability: 10g
Update Time: 2025-06-29

Product Details

Product Name: GW-803430 CAS No.: 515141-51-2
Purity: 98.07% Supply Ability: 10g
Release date: 2025/06/29

Product Introduction

Bioactivity

NameGW-803430
DescriptionGW-803430 (GW-3430) is an orally active and selective melanin-concentrating hormone receptor 1 (MCH R1) antagonist used in the study of obesity.
In vitroGW-803430 exhibits significant antagonistic activity against the action of MCH on the MCHR1 receptor with an IC50 value of approximately 13 nM. [2]
In vivoGW-803430 administered orally once daily at doses of 0.3, 3, and 15 mg/kg induced significant and sustained dose-dependent body weight loss compared to controls. GW-803430 has a favorable pharmacokinetic profile with a bioavailability of 31%, a half-life of 11 hours, and has been shown to exhibit excellent brain penetration in mice with a brain to plasma concentration ratio of 6:1, and is therefore considered an ideal compound. [1]
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 10 mg/mL (20.75 mM), Sonication is recommended.
KeywordsMelaninconcentratingHormoneReceptor(MCHR) | MelaninconcentratingHormoneReceptor | Melaninconcentrating Hormone Receptor (MCHR) | Melanin-concentrating Hormone Receptor | MCHR | MCH1-R | MCH R1 | GW-803430 | GW 803430 | GW 3430
Inhibitors RelatedMCH(human, mouse, rat) | MCHR1 antagonist 2 | ATC 0175 hydrochloride | SNAP 94847 | Melanin Concentrating Hormone, salmon acetate | Neuropeptide EI, rat acetate | PG 931 acetate | TC-MCH 7c | SNAP 94847 hydrochloride | [Ala17]-MCH acetate
Related Compound LibrariesBioactive Compound Library | Bioactive Compounds Library Max

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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