GNA12 Protein, Mouse, Recombinant (His & Myc) NEW
| Price | $2530 |
| Package | 1mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-06-24 |
Product Details
| Product Name: GNA12 Protein, Mouse, Recombinant (His & Myc) | Supply Ability: 10g |
| Release date: 2025/06/24 |
Product Introduction
Bioactivity
| Name | GNA12 Protein, Mouse, Recombinant (His & Myc) |
| Description | Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Activates effector molecule RhoA by binding and activating RhoGEFs (ARHGEF12/LARG). GNA12-dependent Rho signaling subsequently regulates transcription factor AP-1 (activating protein-1). GNA12-dependent Rho signaling also regulates protein phosphatese 2A activation causing dephosphorylation of its target proteins. Promotes tumor cell invasion and metastasis by activating RhoA/ROCK signaling pathway and up-regulating proinflammatory cytokine production. Inhibits CDH1-mediated cell adhesion in process independent from Rho activation. Together with NAPA promotes CDH5 localization to plasma membrane. May play a role in the control of cell migration through the TOR signaling cascade. |
| Storage | Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | Gα12 | Guanine nucleotide-binding protein subunit α-12 | Guanine nucleotide-binding protein subunit a-12 | G-protein subunit α-12 | G-protein subunit a-12 | Gna 12 | Ga12 | G α-12 | G α12 | G alpha12 | G a-12 | G a12 |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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