Glafenine Hydrochloride NEW
| Price | $33 | $48 |
| Package | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-04-27 |
Product Details
| Product Name: Glafenine Hydrochloride | CAS No.: 65513-72-6 |
| Purity: 98.91% | Supply Ability: 10g |
| Release date: 2025/04/27 |
Product Introduction
Bioactivity
| Name | Glafenine Hydrochloride |
| Description | Glafenine Hydrochloride is an anti-inflammatory agent. |
| Cell Research | Glafenine hydrochloride is added to the culture medium of the smooth muscle cells at three concentrations (10 μM, 50 μM, 100 μM). After 4 days of treatment, cells are harvested and the absolute cell number is counted[3]. |
| In vitro | Glafenine enhances the surface expression of mutant Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) in baby hamster kidney (BHK) cells, achieving 40% of the expression levels seen in wild-type CFTR[2]. Additionally, Glafenine hydrochloride suppresses the proliferation and clonogenic capabilities of human aortic smooth muscle cells (haSMCs) and endothelial cells (ECs) in a dose-responsive manner, leading to a blockade at the G2/M phase of the cell cycle and a decline in the G1 phase. Moreover, it dose-dependently impairs the migratory capacity of haSMCs and decreases the level of the extracellular matrix protein tenascin[3]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 60 mg/mL (146.61 mM), Sonication is recommended. |
| Keywords | Inhibitor | inhibit | Glafenine Hydrochloride | Glafenine | Glafenin Hydrochloride | Glafenin | ABCG2 |
| Inhibitors Related | Novobiocin Sodium | Prazosin hydrochloride | Thiethylperazine dimaleate | Glipizide | Vismodegib | Vigabatrin | CCTA-1523 | Erythrodiol | Chlorpropamide | Probucol | DIDS sodium salt | Acridone |
| Related Compound Libraries | Anti-COVID-19 Compound Library |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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