
GITR Ligand/TNFSF18 Protein, Cynomolgus, Recombinant (His) NEW
Price | $3220 |
Package | 1mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2025-07-19 |
Product Details
Product Name: GITR Ligand/TNFSF18 Protein, Cynomolgus, Recombinant (His) | Supply Ability: 10g |
Release date: 2025/07/19 |
Product Introduction
Bioactivity
Name | GITR Ligand/TNFSF18 Protein, Cynomolgus, Recombinant (His) |
Description | TNFSF18 is a single-pass type II membrane protein. It is expressed at high levels in the small intestine, ovary, testis, kidney and endothelial cells. TNFSF18 cytokine binds to TNFRSF18/AITR/GITR. It regulates T-cell responses, and functions as costimulator and lower the threshold for T-cell activation and T-cell proliferation. It is Important for interactions between activated T-lymphocytes and endothelial cells and Promotes leukocyte adhesion to endothelial cells. TNFSF18 mediates activation of NF-kappa-B. As Triggers increased phosphorylation of STAT1 and up-regulates expression of VCAM1 and ICAM1. It also regulates migration of monocytes from the splenic reservoir to sites of inflammation. |
Storage | Shipping with blue ice/Shipping at ambient temperature. |
Keywords | TNFSF-18 | TNFSF 18 | TL-6 | TL 6 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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