Product Details
| Product Name:
GET73 |
CAS No.:
202402-01-5 |
| Purity:
99.54% |
Supply Ability:
10g |
| Release date:
2025/07/15 |
Product Introduction
Bioactivity
| Name | GET73 |
| Description | GET73 (Gamma hydroxybutyric acid analogue) is an negative allosteric modulator of mGluR5. GET73 is a naturally occurring neurotransmitter. GET73 has anti-alcohol and anxiolytic properties. |
| In vitro | GET73 (1 μM, 10 μM; 1 hour) 1 hour before and during chronic ethanol exposure prevents ethanol-induced a reduction of cell viability, an alteration of cytoskeleton, an increase of reactive oxygen species production and a decrease in extracellular glutamate levels. |
| In vivo | GET73 exerts an anxiolytic effect in Sprague-Dawley rats exposed to the elevated plus maze (EPM) test. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice./Shipping at ambient temperature. |
| Solubility Information | DMSO : 97 mg/mL (352.38 mM), Sonication is recommended.
|
| Keywords | γ-hydroxybutyric acid | neuroprotective | mGluR5 | Inhibitor | inhibit | glutamate | GHB | GET-73 | GET73 | anxiolytic | anti-alcohol |
| Inhibitors Related | IDRA-21 | Urethane | Decanoic Acid | Xanthurenic Acid | L-Cysteic acid monohydrate | DCB | Evans blue | L-Glutamine | Direct Blue 1 | L-Glutamic acid monosodium salt | Piracetam | O-Phospho-L-serine |
| Related Compound Libraries | Anti-Neurodegenerative Disease Compound Library | Bioactive Compound Library | Neuronal Signaling Compound Library | Membrane Protein-targeted Compound Library | Glutamine Metabolism Compound Library | Drug Repurposing Compound Library | NO PAINS Compound Library | Clinical Compound Library | Bioactive Compounds Library Max | Fluorochemical Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
| Product name |
Price |
|
Suppliers |
Update time |
|
|
$59.00/1mg |
VIP5Y
|
TargetMol Chemicals Inc.
|
2025-07-15 |
United States