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Postion:Product Catalog >GDC-0834 Racemate
GDC-0834 Racemate
  • GDC-0834 Racemate

GDC-0834 Racemate NEW

Price $98 $214 $723
Package 2mg 5mg 50mg
Min. Order:
Supply Ability: 10g
Update Time: 2025-07-22

Product Details

Product Name: GDC-0834 Racemate CAS No.: 1133432-46-8
Supply Ability: 10g Release date: 2025/07/22

Product Introduction

Bioactivity

NameGDC-0834 Racemate
DescriptionGDC-0834 (racemate) is the racemate form of GDC-0834, an effective and selective BTK inhibitor.
In vitroGDC-0834 inhibited BTK (IC50s: 5.9 and 6.4 nM in biochemical and cellular assays) and (IC50s: 1.1 and 5.6 μM in mouse and rat) [1].
In vivoAdministration of GDC-0834 (30-100 mg/kg) in a rat collagen-induced arthritis (CIA) model resulted in a dose-dependent decrease of ankle swelling and reduction of morphologic pathology [1]. GDC-0834 exhibited low clearance in PXB chimeric mice with humanized liver. GDC-0834 plasma concentrations in humans were below the limit of quantitation (<1 ng/ml) in most samples from the cohorts dosed orally at 35 and 105 mg [2].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility InformationDMSO : 49 mg/mL (82.11 mM), Sonication is recommended.
KeywordsGDC-0834 Racemate | GDC 0834 Racemate | GDC0834 Racemate

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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