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Postion:Product Catalog >Biochemical Engineering>Polypeptide>Gastric Juice Peptide Fragment trifluoroacetate salt
Gastric Juice Peptide Fragment trifluoroacetate salt
  • Gastric Juice Peptide Fragment trifluoroacetate salt
  • Gastric Juice Peptide Fragment trifluoroacetate salt
  • Gastric Juice Peptide Fragment trifluoroacetate salt

Gastric Juice Peptide Fragment trifluoroacetate salt

Price $10
Package 1kg
Min. Order: 1kg
Supply Ability: Ex 20 tons
Update Time: 2022-10-14

Product Details

Product Name: Gastric Juice Peptide Fragment trifluoroacetate salt CAS No.: 137525-51-0
Min. Order: 1kg Purity: 99%
Supply Ability: Ex 20 tons Release date: 2022/10/14

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Use of Gastric Juice Peptide Fragment trifluoroacetate salt

BPC 157 is a stable gastric pentadecapeptide and a partial sequence of the human gastric juice protein BPC. BPC 157 is an anti-ulcer peptidergic agent with no reported toxicity. BPC 157 links inflammatory bowel disease and multiple sclerosis[1][2].

Names

NameBpc 15
SynonymMore Synonyms

  Biological Activity

DescriptionBPC 157 is a stable gastric pentadecapeptide and a partial sequence of the human gastric juice protein BPC. BPC 157 is an anti-ulcer peptidergic agent with no reported toxicity. BPC 157 links inflammatory bowel disease and multiple sclerosis[1][2].
Related Catalog
Research Areas >> Inflammation/Immunology
Target

Human Endogenous Metabolite

In VivoBPC 157 successfully heals the intestinal anastomosis, gastrocutaneous, duodenocutaneous and colocutaneous fistulas in rats, as well as interacting with the NO-system[1]. BPC 157 (10 μg/kg, 10 ng/kg) is applied either intraperitoneally once time daily (first application immediately after surgery, last at 24 hours before sacrifice) or per-orally in drinking water (0.16 μg/ml/12 ml/day till the sacrifice). A multiple sclerosis suited toxic rat model, cuprizone (compared with standard, a several times higher regimen, 2.5% of diet regimen + 1 g/kg intragastrically/day) was combined with BPC 157 (in drinking water 0.16 μg or 0.16 ng/ml/12 ml/day/rat + 10 μg or 10 ng/kg intragastrically/day) till the sacrifice at day 4. In general, the controls could not heal cysteamine colitis and colon-colon anastomosis. BPC 157 induced an efficient healing of both at the same time[2].
Solvent
In Vitro:

DMSO : 100 mg/mL (70.45 mM; Need ultrasonic)

In Vivo:

1.

Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

Solubility: ≥ 2.5 mg/mL (1.76 mM); Clear solution


2.

Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

Solubility: ≥ 2.5 mg/mL (1.76 mM); Clear solution


3.

Add each solvent one by one:  10% DMSO    90% corn oil

Solubility: ≥ 2.5 mg/mL (1.76 mM); Clear solution


Solubility1 mM0.7045 mL3.5223 mL7.0445 mL5 mM0.1409 mL0.7045 mL1.4089 mL10 mM0.0704 mL0.3522 mL0.7045 mL
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

ShippingRoom temperature
References

[1]. Sikiric P, et al. Stable gastric pentadecapeptide BPC 157: novel therapy in gastrointestinal tract. Curr Pharm Des. 2011;17(16):1612-1632.

[2]. Klicek R, et al. Stable gastric pentadecapeptide BPC 157 heals cysteamine-colitis and colon-colon-anastomosis and counteracts cuprizone brain injuries and motor disability. J Physiol Pharmacol. 2013;64(5):597-612.

 Chemical & Physical Properties

Density1.4±0.1 g/cm3
Boiling Point1802.9±65.0 °C at 760 mmHg
Molecular FormulaC62H98N16O22
Molecular Weight1419.536
Flash Point1044.2±34.3 °C
Exact Mass1418.704102
LogP-2.41
Vapour Pressure0.0±0.6 mmHg at 25°C
Index of Refraction1.576

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