G0-C14 NEW
| Price | $106 | $237 | $379 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-05-01 |
Product Details
| Product Name: G0-C14 | CAS No.: 1510653-27-6 |
| Purity: 98% | Supply Ability: 10g |
| Release date: 2025/05/01 |
Product Introduction
Bioactivity
| Name | G0-C14 |
| Description | G0-C14 is a cationic lipid-like molecule commonly used for synthesizing nanoparticles and vaccine delivery. |
| In vitro | G0-C14 has a highly efficient encapsulation ability for mRNA and pDNA, and the encapsulation efficiency can reach more than 95%. [1] The nanoparticles were prepared as follows:[1] 1. PolyHCPT and DSPE-PEG3K were dissolved in DMF and prepared into a homogeneous solution with a concentration of 5 mg/mL. 2. a mixture of siRNA (0.1 nmol/μL in water) and G0-C14 (5 mg/mL, dissolved in DMF) was prepared and mixed according to different N/P molar ratios. Subsequently, this mixture is combined with PolyHCPT and DSPE-PEG3K solutions. 3. The above mixture was added dropwise to 5 mL of deionized water at 1000 rpm with vigorous stirring. 4. The resulting NPs dispersion was transferred to an ultrafiltration unit. 5. Centrifuge at 2800 rpm for 8 minutes at room temperature to remove organic solvents and free compounds. |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 80 mg/mL (44.67 mM), Sonication is recommended. |
| Inhibitors Related | Dihexadecyl hydrogen phosphate | DSPE-PEG 2000 | NHLP-002 | DSPE-PEG-Azide (MW 2000) | POPG sodium salt | NHLP-001 | DHAPC | DSPG sodium | Vaxfectin | 5A2-SC8 | 4A3-SC8 | Dehydroergosterol |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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