
Fz7-21 NEW
Price | $68 | $179 | $289 |
Package | 1mg | 5mg | 10mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2025-05-13 |
Product Details
Product Name: Fz7-21 | CAS No.: 2247635-23-8 |
Purity: 99.8% | Supply Ability: 10g |
Release date: 2025/05/13 |
Product Introduction
Bioactivity
Name | Fz7-21 |
Description | Fz7-21 ((Ac)-LPSDDLEFWCHVMY-NH2) is a peptide antagonist of FZD7 . It antagonises WNT3A-induced Wnt-β-catenin signalling in HEK293 expressing FZD7. Fz7-21 impairs Wnt/β-catenin signaling in HEK293 cells stimulated with exogenous WNT3A (IC50=100 nM) or transfected with a construct expressing WNT3A or WNT1. Fz7-21 also blocks WNT3A-mediated stabilization of β-catenin in mouse L cells (IC50=50 nM). |
Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : 10 mM, Sonication is recommended. |
Keywords | βcatenin | Wnt–β-catenin | Wnt/β-catenin | Wnt/betacatenin | Wnt/b-catenin | Wnt | mouse FZD7 CRD | lipid-binding groove | intestinal organoids | Inhibitor | inhibit | human FZD7 CRD | FZD7 CRD | FZD7 | Fz7-21 | Fz-7-21 | Fz721 | Fz7 21 | conformation | beta-catenin | betacatenin | bcatenin |
Inhibitors Related | Urea | PRI-724 | Wnt pathway activator 1 | TNIK-IN-3 | L-quebrachitol | EMT inhibitor-1 | CHIR-99021 | XAV-939 | TNIK-IN-2 | Nefopam hydrochloride | KY-05009 | Bisdemethoxycurcumin |
Related Compound Libraries | Neural Regeneration Compound Library | Reprogramming Compound Library | Bioactive Compound Library | Anti-Alzheimer's Disease Compound Library | Anti-Ovarian Cancer Compound Library | Peptide Compound Library | Inhibitor Library | Bioactive Compounds Library Max | Cytoskeletal Signaling Pathway Compound Library | Anti-Cancer Compound Library | Wnt/Hedgehog/Notch Compound Library | Neuronal Differentiation Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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