FX-06 NEW
| Price | Get Latest Price | |
| Package | 5mg | 50mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-07-17 |
Product Details
| Product Name: FX-06 | CAS No.: 88650-17-3 |
| Supply Ability: 10g | Release date: 2025/07/17 |
Product Introduction
Bioactivity
| Name | FX-06 |
| Description | FX-06 (Fibrin-derived peptide Bβ15-42) is derived from the fibrin Bbeta chain and interacts with VE-cadherin to inhibit leukocyte transmigration while initiating VE-cadherin-mediated signaling pathways. This compound is utilized in researching ischemia/reperfusion injury and Dengue shock syndrome (DSS) [1] [2] [4]. |
| In vitro | FX-06 (50 μM, 3 days) inhibits D2HG synthesis in HEK-293T cells expressing mutant IDH1 R132H [2]. |
| In vivo | FX06, administered intravenously at 2.4 mg/kg as a bolus, notably enhances pulmonary and circulatory function in a porcine model of hemorrhagic shock and reperfusion [3]. The same dosage, given intraperitoneally twice daily, increases survival rates and mitigates capillary leakage in Dengue shock syndrome mouse models [4]. When administered at 3.6 mg/kg intravenously, FX06 safeguards against ischemia/reperfusion (I/R)-induced renal damage in mice, promoting epithelial cell proliferation and facilitating tissue repair [5]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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