Product Details
Product Name:
EMI56 |
CAS No.:
2414374-41-5 |
Supply Ability:
10g |
Release date:
2025/07/24 |
Product Introduction
Bioactivity
Name | EMI56 |
Description | EMI56, a derivative of EMI1, exhibits enhanced potency against mutant EGFR compared to EMI1. Additionally, EMI56 effectively inhibits EGFR triple mutants[1]. |
In vitro | EMI56 inhibits EGFR ex19del/T790M/C797S and EGFR L858R/T790M/C797S and can be used in research of mutant EGFR-associated, drug-resistant non-small-cell lung cancer (NSCLC)[1]. EMI56 (10, 15, 20 μM; 2 h of treatment) strongly inhibits total EGFR levels, activation, and downstream signaling in PC9 EGFR ex19del/T790M/C797S cells[1]. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Solubility Information | DMSO : 50 mg/mL (143.51 mM), Sonication and heating to 60℃ are recommended.
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Keywords | EMI 56 | EMI56 | EMI-56 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
Product name |
Price |
|
Suppliers |
Update time |
|
$/ |
|
Anhui Ruihan Technology Co., Ltd
|
2023-08-21 |