EGFR-IN-11 NEW
| Price | $47 | $118 | $202 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-04-30 |
Product Details
| Product Name: EGFR-IN-11 | CAS No.: 2463200-44-2 |
| Purity: 99.37% | Supply Ability: 10g |
| Release date: 2025/04/30 |
Product Introduction
Bioactivity
| Name | EGFR-IN-11 |
| Description | EGFR-IN-11 is a selective inhibitor of EGFR-tyrosine kinase and induces cell apoptosis. EGFR-IN-11 inhibits triple mutant EGFRL858R/T790M/C797S with an IC50 of 18 nM and arrests cell cycle at G0/G1. |
| In vitro | EGFR-IN-11 (0.1 nM-10 μM) shows anti-proliferation with IC50s of 0.88 nM, 0.20 μM and 2.91 μM for HCC827, H1975 and A549 cells. EGFR-IN-11 (10nM-10 μM) suppresses the phosphorylation of EGFR in a concentration-dependent manner in the HCC827, H1975 and A549 cells[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 112.5 mg/mL (196.1 mM ), Sonication is recommended. |
| Keywords | EGFRL858R/T790M/C797S | EGFR-IN-11 | EGFRIN11 | EGFR IN 11 | EGFR |
| Inhibitors Related | Osimertinib | Lidocaine Hydrochloride hydrate | Lapatinib | Afatinib Dimaleate | Erlotinib hydrochloride | Erlotinib | Neratinib | Chalcone | Osimertinib mesylate | Genistein | Khellin | Gefitinib |
| Related Compound Libraries | Anti-Lung Cancer Compound Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Kinase Inhibitor Library | Tyrosine Kinase Inhibitor Library | JAK-STAT Compound Library | Angiogenesis related Compound Library | Inhibitor Library | Stem Cell Differentiation Compound Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
Recommended supplier
| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $2785.00/50mg |
VIP1Y
|
TargetMol Chemicals Inc.
|
2025-04-28 | |
| $98.00/1mg |
VIP5Y
|
TargetMol Chemicals Inc.
|
2025-05-20 | |
| $0.00/1kg |
VIP3Y
|
Henan Aochuang Chemical Co.,Ltd.
|
2022-09-30 | |
| $47.00/1mg |
VIP5Y
|
TargetMol Chemicals Inc.
|
2025-07-16 |
United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
INQUIRY