Product Details
Product Name:
eCF506 |
CAS No.:
1914078-41-3 |
Purity:
98.00% |
Supply Ability:
10g |
Release date:
2025/07/24 |
Product Introduction
Bioactivity
Name | eCF506 |
Description | eCF506 is a potent and selective inhibitor of SRC (IC50 < 0.5 nM) |
In vitro | eCF506 can inhibit tyrosine kinase Src with IC50 value less than 0.5 nM. |
In vivo | METHODS: Immunodeficient Rag2-Il2rg double knockout mice were implanted with PX459v2 and ILK gRNA 2 tumors and then given bosutinib (75 mg/kg) or eCF506 (40 mg/kg) once daily by oral gavage, and tumor volume growth was observed.
RESULTS eCF506 treatment completely blocked the growth of ILK gRNA and PX459v2 tumors in the mouse model. [2] |
Storage | keep away from moisture,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Solubility Information | DMSO : 1 mg/mL (1.96 mM), Sonication is recommended.
|
Keywords | Src | Inhibitor | inhibit | eCF-506 | eCF506 | eCF 506 |
Inhibitors Related | Nintedanib | Vemurafenib | SI-2 hydrochloride | Staurosporine | Tandutinib | Bosutinib hydrate | Ibrutinib | Dasatinib | Ponatinib | Pelitinib | Tofacitinib | Masitinib |
Related Compound Libraries | Reprogramming Compound Library | Anti-Pancreatic Cancer Compound Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Kinase Inhibitor Library | Tyrosine Kinase Inhibitor Library | Anti-Cancer Metabolism Compound Library | Angiogenesis related Compound Library | Inhibitor Library | NO PAINS Compound Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
Product name |
Price |
|
Suppliers |
Update time |
|
$/ |
|
Anhui Ruihan Technology Co., Ltd
|
2023-08-21 |