![(E)-[6]-Dehydroparadol](/ProductImageEN1/2025-06/Large/9d2ea648-b062-4527-bad4-bdb3743c2fcb.png)
(E)-[6]-Dehydroparadol NEW
Price | $37 | $85 | $118 |
Package | 1mg | 5mg | 10mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2025-06-21 |
Product Details
Product Name: (E)-[6]-Dehydroparadol | CAS No.: 878006-06-5 |
Purity: 99.87% | Supply Ability: 10g |
Release date: 2025/06/21 |
Product Introduction
Bioactivity
Name | (E)-[6]-Dehydroparadol |
Description | (E)-[6]-Dehydroparadol ((6)-Dehydroparadol), an oxidative metabolite of [6]-Shogaol, is a potent Nrf2 activator. |
In vitro | (E)-[6]-Dehydroparadol (5-80 μM; 24 h) inhibits the growth of HCT-116 and H-1299 cells, with IC50s of 43.02 and 41.59 μM, respectively. (E)-[6]-Dehydroparadol (10-40 μM; 24 h) induces apoptosis in HCT-116 and H-1299 cells[1]. |
In vivo | (E)-[6]-Dehydroparadol at a concentration of 5 μM for 24 hours increases the fluorescence signal of Tg[glutathione S-transferase pi 1 (gstp1):green fluorescent protein (GFP)] in Tg(gstp1:GFP) transgenic zebrafish embryos. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice./Shipping at ambient temperature. |
Solubility Information | DMSO : 120 mg/mL (434.2 mM), Sonication is recommended. |
Keywords | Nrf2 | HCT-116 | [6]-Dehydroparadol |
Inhibitors Related | TBHQ | L-Cystine dihydrochloride | Mangiferin | Dimethyl fumarate | Methyl 3,4-dihydroxybenzoate | Pyridoxine | Resveratrol | Curcumin | Ezetimibe | Oltipraz | 4-hydroxyphenylacetic acid | Pyridoxine hydrochloride |
Related Compound Libraries | Bioactive Compound Library | Immunology/Inflammation Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Transcription Factor-Targeted Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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